The American journal of emergency medicine
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Routine evaluation with CTA for patients with isolated lower extremity penetrating trauma and normal ankle-brachial-indices (ABI) remains controversial. While prior literature has found normal ABI's (≥0.9) and a normal clinical examination to be adequate for safe discharge, there remains concern for missed injuries which could lead to delayed surgical intervention and unnecessary morbidity. Our hypothesis was that routine CTA after isolated lower extremity penetrating trauma with normal ABIs and clinical examination is not cost-effective. ⋯ Patients with isolated, penetrating lower extremity trauma with normal ABIs and clinical examination do not warrant routine CTA as there is no benefit with increased costs.
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Low back pain is a common reason for presentation to the Emergency Department (ED). However, there are limited large-scale, recent data on the epidemiology, disposition, and medication administration for this condition. The objective of this was to assess the incidence, admission rates, medication administrations, and discharge prescriptions among ED visits for low back pain in the United States. ⋯ Low back pain represents a common reason for presentation to the ED, and admissions have been increasing over time. Opioids remain the most common ED medication, whereas muscle relaxants have arisen as the most common discharge prescription. These findings can help inform health policy decisions, resource allocation, and evidence-based interventions for medication administration.
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Large Language Models (LLMs) represent a transformative advancement in the preparation of medical scientific manuscripts, offering significant benefits such as reducing drafting time, enhancing linguistic precision, and aiding non-native English speakers. These models, which generate text by learning from extensive datasets, can streamline the publication process and maintain consistency across collaborative projects. ⋯ Ethical concerns about accuracy, authorship, and transparency need to be carefully considered. The American Journal of Emergency Medicine has adopted a policy permitting LLM use with full disclosure and author responsibility, emphasizing the need for ongoing policy evolution in response to technological advancements.
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Tempol, a synthetic antioxidant compound, has received significant attention for its potential therapeutic applications in recent years, especially against ischemia/reperfusion (I/R) injury. The aim of the present research was to assess the protective effects of Tempol on testicular I/R injury caused by testicular torsion and detorsion (T/D) in rats. ⋯ These findings provide strong evidence that Tempol can effectively prevent testicular I/R injury.