Resuscitation
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Observational Study
Organ support therapy in the intensive care unit and return to work in out-of-hospital cardiac arrest survivors-A nationwide cohort study.
With increased survival after out-of-hospital cardiac arrest (OHCA), impact of the post-resuscitation course has become important. Among 30-day OHCA survivors, we investigated associations between organ support therapy in the Intensive Care Unit (ICU) and return to work. ⋯ In 30-day survivors of OHCA, number of organ support therapies and in particular need of RRT were associated with reduced rate of return to work, although more than half of these latter patients still returned to work.
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Observational Study
Women have worse cognitive, functional, and psychiatric outcomes at hospital discharge after cardiac arrest.
To examine gender differences among cardiac arrest (CA) survivors' cognitive, functional, and psychiatric outcomes at discharge. ⋯ Women have worse cognitive, functional, and psychiatric outcomes at hospital discharge after cardiac arrest than men. Identifying factors contributing to these differences is of great importance in cardiac arrest outcomes research.
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To evaluate the performance of a state-of-the-art cardiopulmonary resuscitation (CPR) artefact suppression method by assessing to what extent the filtered electrocardiogram (ECG) can be correctly diagnosed by emergency medicine doctors. ⋯ Clinicians outperformed the SAA, but specificities remained below the specifications recommended by the American Heart Association. Visual assessment of the filtered ECG by clinicians is not reliable enough, and varies greatly among clinicians. Results considerably improve by considering the consensus decision of a pool of clinicians.
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Observational Study
Non-invasive characterization of hemodynamics in adult out-of-hospital cardiac arrest patients soon after return of spontaneous circulation.
Little is known about hemodynamics in adult, out-of-hospital (OHCA) patients following return of spontaneous circulation (ROSC). A 1994 study when "high-dose epinephrine" use was common showed consistently elevated systemic vascular resistance (SVR) lasting ≥6 h in 49 adult patients after return of spontaneous circulation (ROSC). ⋯ A heterogeneous range of hemodynamic states exist post-ROSC rather than consistent vasoconstriction. Adequately powered, randomized clinical trials will be needed to determine whether noninvasively-derived, hemodynamic-directed therapy can play a role in improving neurologically-intact survival following OHCA in adults.