Resuscitation
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Review Meta Analysis
Diagnostic performance of optic nerve sheath diameter for predicting neurologic outcome in post-cardiac arrest patients: A systematic review and meta-analysis.
We evaluated the diagnostic performance of optic nerve sheath diameter (ONSD) for prediction of neurologic outcome in post-cardiac arrest patients and relative prediction performance according to ONSD measurement modality. ⋯ ONSD may be useful for predicting neurologic outcomes in post-cardiac arrest patients. Measuring the ONSD specifically using ocular ultrasound, application in patients with cardiac-origin cardiac arrest, and using the Glasgow-Pittsburgh Cerebral Performance Categories for neurologic outcome evaluation are recommended for more accurately predicting neurologic outcomes.
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Randomized Controlled Trial Multicenter Study
Early blood transcriptomic signature predicts patients' outcome after out-of-hospital cardiac arrest.
Early prognostication is a major challenge after out-of-hospital cardiac arrest (OHCA). ⋯ A transcriptomic signature involving a counterbalance between adaptive and innate immune responses is able to predict neurological outcome very early after hospital admission after OHCA. This deserves confirmation in a larger population.
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To systematically evaluate the literature on interventions that improve skills retention following advanced structured resuscitation training programs designed for healthcare professionals. ⋯ Simulation-based interventions, refresher courses and adjustments to the content delivery of advanced structured resuscitation training courses were found to have the greatest impact on skills retention. However, due to significant heterogeneity and methodological flaws in the available studies, no definitive conclusions can be made regarding other interventions. Overall, there is a paucity of skills retention research and further high-quality randomized controlled trials are needed to determine the optimal intervention and design for resuscitation training that would maximize skills retention.
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Randomized Controlled Trial Multicenter Study
The effect of an International competitive leaderboard on self-motivated simulation-based CPR practice among healthcare professionals: A randomized control trial.
Little is known about how best to motivate healthcare professionals to engage in frequent cardiopulmonary resuscitation (CPR) refresher skills practice. A competitive leaderboard for simulated CPR can encourage self-directed practice on a small scale. The study aimed to determine if a large-scale, multi-center leaderboard improved simulated CPR practice frequency and CPR performance among healthcare professionals. ⋯ A competitive leaderboard was not associated with an increase in self-directed simulated CPR practice or improved performance.
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Multicenter Study
Time of on-scene resuscitation in out of-hospital cardiac arrest patients transported without return of spontaneous circulation.
In out-of-hospital cardiac arrest (OHCA), return of spontaneous circulation (ROSC) on scene occurs only in a minority of patients. The optimal duration of resuscitation on scene before transport with ongoing cardiopulmonary resuscitation (CPR) is unknown. ⋯ In OHCA patients transported with ongoing CPR the survival rate significantly declines when time on scene increases.