Resuscitation
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Editorial Comment
Moving beyond survival and navigating survivorship: mind the gaps!
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Review Meta Analysis
Targeted Temperature Management in Adult Cardiac Arrest: Systematic Review and Meta-Analysis.
To perform a systematic review and meta-analysis on targeted temperature management in adult cardiac arrest patients. ⋯ Among adult patients with cardiac arrest, the use of targeted temperature management at 32-34 °C, when compared to normothermia, did not result in improved outcomes in this meta-analysis. There was no effect of initiating targeted temperature management prior to hospital arrival. These findings warrant an update of international cardiac arrest guidelines.
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Observational Study
Multimodal Monitoring Including Early EEG Improves Stratification of Brain Injury Severity after Pediatric Cardiac Arrest.
Assessment of brain injury severity early after cardiac arrest (CA) may guide therapeutic interventions and help clinicians counsel families regarding neurologic prognosis. We aimed to determine whether adding EEG features to predictive models including clinical variables and examination signs increased the accuracy of short-term neurobehavioral outcome prediction. ⋯ The addition of standardized EEG Background Categories to readily available CA variables significantly improved early stratification of brain injury severity after pediatric CA.
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To compare the risk of in-hospital mortality and morbidity between outborn and inborn neonates treated with whole body hypothermia. ⋯ Outborn status was not significantly associated with increased in-hospital mortality among neonates treated with whole body hypothermia. However, outborn neonates were more likely to have seizures, receive anticonvulsant treatment, and undergo gastrostomy tube placement. Further study is needed to better understand the etiologies of these outcome disparities and potential implications for long-term neurodevelopmental outcomes.