Resuscitation
-
Randomized Controlled Trial Comparative Study
Effect of a reminder video using a mobile phone on the retention of CPR and AED skills in lay responders.
Skills related to cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) use by lay responders decay rapidly after training, and efforts are required to maintain competence among trainees. We examined whether repeated viewing of a reminder video on a mobile phone would be an effective means of maintaining CPR and AED skills in lay responders. ⋯ Repeated viewing of a reminder video clip on a mobile phone increases retention of CPR and AED skills in lay responders.
-
Comparative Study
Shock advisory system with minimal delay triggering after end of chest compressions: accuracy and gained hands-off time.
Shortening hands-off intervals can improve benefits from defibrillation. This study presents the performance of a shock advisory system (SAS), which aims to decrease the pre-shock pauses by triggering fast rhythm analysis at minimal delay after end of chest compressions (CC). ⋯ This study indicates that shortening the pre-shock hands-off pause by more efficient management of the SAS process in AEDs is possible. For analysis duration of 5 s (7 s), the delay between the end of chest compressions and the shock advice can be reduced by 10.5 s (8.5 s) median, while AHA requirements for rhythm detection accuracy are met. The use of this solution in AEDs could provide more reliable rhythm analysis than methods applying filtering techniques during CC.
-
Sodium nitroprusside-enhanced CPR, or SNPeCPR, consists of active compression-decompression CPR with an impedance threshold device, abdominal compression, and intravenous sodium nitroprusside (SNP). We hypothesize that SNPeCPR will improve post resuscitation left ventricular function and neurological function compared to standard (S) CPR after 15 min of untreated ventricular fibrillation in a porcine model of cardiac arrest. ⋯ In this pig model, after 15 min of untreated ventricular fibrillation, SNPeCPR significantly improved 24-hour survival rates, neurologic function and prevented post-resuscitation left ventricular dysfunction compared to S-CPR.
-
Comparative Study
Post-cardiac arrest hyperoxia and mitochondrial function.
Rapid post-ischemic re-oxygenation is necessary to minimize ischemic injury, but itself can induce further reperfusion injury through the induction of reactive oxygen species. Utilization of oxygen within the cell primarily occurs in the mitochondria. The objective of this study was to determine heart mitochondrial function after 1 h of controlled arterial oxygenation following cardiac arrest and restoration of spontaneous circulation (ROSC). We hypothesized that arterial hyper-oxygenation following ROSC would result in greater impairment of heart mitochondrial function. ⋯ Post-ROSC arterial hyperoxia after a short cardiac arrest exacerbates impaired mitochondrial function. The overall clinical significance of these findings is unclear and requires additional work to better understand the role of post-arrest hyperoxia on cardiac and mitochondrial function.