Resuscitation
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Multicenter Study
Electromyographic reactivity measured with scalp-EEG contributes to prognostication after cardiac arrest.
To assess whether stimulus-induced modifications of electromyographic activity observed on scalp EEG have a prognostic value in comatose patients after cardiac arrest. ⋯ Taking EMG into account when assessing reactivity of EEG seems to reduce false negative predictions for identifying patients with favorable outcome after cardiac arrest.
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Multicenter Study
Text message alert system and resuscitation outcomes after out-of-hospital cardiac arrest: A before-and-after population-based study.
This study aimed to investigate the association of a resuscitation bundle intervention including text message (TM) alert system and bystander cardiopulmonary resuscitation (CPR) and outcomes of out-of-hospital cardiac arrest (OHCA). ⋯ The bundle intervention including TM alert service for OHCA was associated with better survival outcomes through an increase in bystander CPR. Clinical trials registration; NCT02010151.
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Multicenter Study
Prognostication after cardiac arrest: Results of an international, multi-professional survey.
We explored preferences for prognostic test performance characteristics and error tolerance in decisions regarding withdrawal or continuation of life-sustaining therapy (LST) after cardiac arrest in a diverse cohort of medical providers. ⋯ Medical providers are comfortable with low acceptable FPR for withdrawal (≤0.1%) and continuation (≤1%) of LST after cardiac arrest. These FPRs may be lower than can be achieved with current prognostic modalities.
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Multicenter Study
Patient and hospital factors predict use of coronary angiography in out-of-hospital cardiac arrest patients.
To describe the association between patient- and hospital-level factors and coronary angiography among patients who suffer out-of-hospital cardiac arrest (OHCA). ⋯ We identified patient- and hospital-level factors that explain some of the variability in the use of coronary angiography for OHCA. Future work should determine which post arrest patients will benefit most from urgent coronary angiography and evaluate knowledge translation strategies to ensure consistent delivery of best practices.
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Randomized Controlled Trial Multicenter Study
Early blood transcriptomic signature predicts patients' outcome after out-of-hospital cardiac arrest.
Early prognostication is a major challenge after out-of-hospital cardiac arrest (OHCA). ⋯ A transcriptomic signature involving a counterbalance between adaptive and innate immune responses is able to predict neurological outcome very early after hospital admission after OHCA. This deserves confirmation in a larger population.