Pediatric dermatology
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Pediatric dermatology · Jul 2013
Case ReportsDermoscopic and histological correlation of an atypical case of pyogenic granuloma.
Pyogenic granuloma (PG) is a common, rapidly growing, benign vascular proliferation of skin and mucous membranes generally showing, on dermoscopy, a typical pattern characterized by a red to dark pink homogeneous area surrounded by a white collarette. A case of PG in a 5-year-old girl showing an atypical dermoscopic pattern characterized by the presence of a central, irregular, whitish-yellow amorphous structure with a peripheral crown of polymorphous, atypical vessels is reported and discussed.
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Pediatric dermatology · May 2013
Case ReportsSpitz nevus arising upon a congenital glomuvenous malformation.
There are several reports of the collision of vascular and pigmentary anomalies (e.g., phakomatosis pigmentovascularis) and the association between congenital melanocytic nevi and infantile hemangiomas. We report a case of Spitz nevus arising in skin overlying a congenital plaque-like glomuvenous malformation (GVM). This is the first report of a Spitz nevus arising in direct contiguity to a GVM.
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Pediatric dermatology · May 2013
Case ReportsInvasive lymphatic malformation (gorham-stout) of the pelvis with prominent skin involvement.
Gorham-Stout syndrome is a rare disease characterized by progressive osteolysis leading to disappearance of the bone. Vascular proliferations have been implicated in the pathogenesis of this syndrome. The case of a 7-year-old girl with a prominent invasive lymphatic malformation on the lumbosacral area and massive osteolysis of the pelvic girdle is reported.
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Pediatric dermatology · May 2013
Case ReportsFacial lichen striatus in children: retracing the lines of Blaschko.
We report seven patients with facial lichen striatus along the lines of Blaschko who presented to our pediatric dermatology unit between 2003 and 2009. The mean age of diagnosis was 4.6 years (range 2.5-9 years). ⋯ This case series describes the distribution, presentation, and natural history of lichen striatus along facial lines of Blaschko. From our experience, clinical diagnosis and monitoring without biopsy is a reasonable approach to the management of uncomplicated lichen striatus, particularly when the face is involved.
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Propranolol has become the treatment of choice of large and complicated infantile hemangiomas. There is a controversy concerning the safety of systemic propranolol. Here we show that topical use of the beta-blocker timolol can also inhibit the growth and promote regression of infantile hemangiomas. ⋯ Even supposing complete absorption of timolol from the occlusive dressing, a maximum dose of 0.25 mg of timolol would result per day and hemangioma. Regression of infantile hemangiomas treated using 0.5% timolol gel in this case series occurred earlier than spontaneous regression which is generally not observed before the age of 9-12 months. The promising results need to be verified in prospective randomized trials on topical beta blocker administration for infantile hemangiomas which should address dose, duration, and mode of application.