Pediatric dermatology
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Pediatric dermatology · Mar 2005
Randomized Controlled Trial Comparative StudyChildren's rating of itch: an experimental study.
Little is known about children's ability to assess itch. The present paper aimed to investigate the discriminative capacity of two itch rating scales in children. Sixty healthy children, 4 to 12 years of age, participated. ⋯ However, children 4 to 5 years of age rated the itch intensity (both scales) less well than those aged 6 to 12 years. The younger age group discriminated between saline and histamine, but not between the different histamine concentrations. In conclusion, children aged 6 to 12 years were able to discriminate between different itch stimulus strengths in a dose-dependent way with a 100-mm visual analog scale and a four-stepped verbal rating scale, indicating the validity of these scales for measurement of experimental itch in children 6 years or older.
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Pediatric dermatology · Nov 2004
Randomized Controlled Trial Comparative Study Clinical TrialEfficacy of a reduced application time of Ovide lotion (0.5% malathion) compared to Nix creme rinse (1% permethrin) for the treatment of head lice.
Our objective was to conduct a randomized, investigator-blinded evaluation of the pediculicidal and ovicidal activity of a reduced application time (20 minutes) of Ovide (0.5% malathion) compared to Nix (1% permethrin) in a south Florida population infested with Pediculus humanus capitis. Either Ovide or Nix was applied according to the label instructions. However, Ovide application time was reduced to 20 minutes. ⋯ The reinfestation rate was 0% with Ovide and 33% with Nix. In conclusion, a 20-minute treatment with Ovide, instead of the approved 8- to 12-hour application, cured 40 of 41 subjects (98%), demonstrating superior efficacy to Nix. The poor efficacy of Nix confirms the resistance of head lice to permethrin in south Florida.
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Pediatric dermatology · Jul 2003
Randomized Controlled Trial Multicenter Study Clinical TrialLidocaine iontophoresis for topical anesthesia before dermatologic procedures in children: a randomized controlled trial.
Local anesthesia by injection in pediatric patients undergoing dermatologic procedures is not well received because of the pain of injection and the fear of needles. Lidocaine iontophoresis is a method of topical anesthesia where lidocaine is driven into the skin under the influence of electric current. We performed a prospective double-blind, placebo-controlled evaluation of iontophoresis of 2% lidocaine with 1:100,000 epinephrine. ⋯ Blanching and/or erythema occurred in 58 of 60 patients, but resolved within 1 hour in all patients. There were no other adverse events. Lidocaine iontophoresis is a safe and effective method of topical anesthesia prior to dermatologic procedures in children.
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Pediatric dermatology · Mar 1998
Randomized Controlled Trial Clinical TrialA double-blind, randomized, placebo-controlled trial of eutectic lidocaine/prilocaine cream 5% (EMLA) for analgesia prior to cryotherapy of warts in children and adults.
Liquid nitrogen cryotherapy is an effective treatment modality for verrucae in children. However, sometimes the pain of the procedure is too much for the young child. In such instances the availability of an effective topical anesthetic would be of tremendous benefit. ⋯ The topical anesthetic was safe and generally well-tolerated. Lidocaine/prilocaine cream 5% may provide some anesthesia in children receiving cryotherapy when the wart is on the palms or soles. Further studies are needed to better understand the site and age specificity of the anesthetic properties of lidocaine/prilocaine cream 5% when used to reduce the pain experienced during cryotherapy of warts.