European journal of anaesthesiology
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Comparative Study
Two distinct application habits for propofol: an observational study.
In total intravenous anaesthesia, two different application modes for propofol are widely used: infusion by means of manually controlled infusion pumps, and infusion by means of microprocessor-controlled infusion pumps operating according to pharmacokinetic algorithms (target controlled infusion, TCI). The parallel use of these two methods in our department by various anaesthetists offered the opportunity to retrospectively compare both application patterns regarding clinical effects and drug consumption. ⋯ Both observed application patterns for propofol showed similar clinical profiles. Using TCI, awakening time was 5 min earlier than with manual infusion mode, thus showing a potential pharmaco-economical advantage in anaesthesias for gynaecological laparoscopy. The detected differences did not have a statistically significant influence on the early postoperative outcome.
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Comparative Study
Continuous mixed venous and central venous oxygen saturation in cardiac surgery with cardiopulmonary bypass.
Replacing mixed venous oxygen saturation (SvO2) monitoring by central venous oxygen saturation (ScvO2) monitoring in order to avoid the use of a pulmonary artery catheter and its related complications is still controversial in the setting of cardiac surgery. The influence of surgery, cardiopulmonary bypass and anaesthesia drugs on the relationship between SvO2 and ScvO2 has never been studied. ⋯ Because of the large interindividual variability in the difference between SvO2 and ScvO2, the measure of ScvO2 should not replace the measure of SvO2 with a pulmonary artery catheter for the management of patients undergoing cardiac surgery with cardiopulmonary bypass.
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Comparative Study
In-vitro evaluation of the PediaSat continuous central venous oxygenation monitoring system.
In-vitro performance of the PediaSat system for continuous monitoring of central venous oxygen saturation by spectrophotometry has been evaluated. ⋯ The current version of the PediaSat system does not reliably reflect S CO-OX O2 values below 70%, but it seems to be a useful tool providing an accurate trend of continuous central venous oxygen saturation.
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Few data are available on the efficacy of noninvasive ventilation (NIV) in postoperative patients with acute respiratory failure (ARF). ⋯ NIV could be considered in postoperative patients who presented with ARF. Nosocomial pneumonia is predictive of NIV failure.