European journal of anaesthesiology
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Assessment of Mallampati class is an integral part of preoperative airway evaluation. Increasing Mallampati class is known to be associated with greater difficulty with intubation, but some cases of airway difficulty in Mallampati 'class zero' patients have been reported. ⋯ A Mallampati class zero per se is not associated with difficult airway unless other airway characteristics contribute to the difficulty. Even though the epiglottis may be large and overhanging, it rarely causes airway difficulty in Mallampati class zero airway.
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Surgery-induced neuroinflammation has been implicated in the development of postoperative cognitive dysfunction (POCD). ⋯ These findings suggest that COX-2-dependent mechanisms may play a role in the development of POCD. This effect may be dependent on the modulation of glial cell activation.
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Letter Case Reports
Anaesthesia and orphan disease: phocomelia--a lesson from the past.