European journal of anaesthesiology
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Comment Letter
Transversus abdominis plane block in inguinal hernia repair.
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Editorial Historical Article
History of anaesthesia: Datex. A Finnish success story in anaesthesia monitoring.
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Observational Study
Central venous-to-arterial carbon dioxide partial pressure difference in early resuscitation from septic shock: A prospective observational study.
Central venous-to-arterial carbon dioxide partial pressure difference (ΔPCO2) can be used as a marker for the efficacy of venous blood in removing the total CO2 produced by the tissues. To date, this role of ΔPCO2 has been assessed only in patients after resuscitation from septic shock with already normalised central venous oxygen saturation (ScvO2 ≥70%). There are no reports on the behaviour of ΔPCO2 and its relationship to cardiac index (CI) and clinical outcome before normal ScvO2 has been achieved. ⋯ Monitoring ΔPCO2 may be a useful tool to assess the adequacy of tissue perfusion during resuscitation. The normalisation of both ΔPCO2 and ScvO2 is associated with a greater decrease in blood lactate concentration than ScvO2 alone. The lactate decrease is an independent predictor of 28-day mortality. Further research is needed to confirm this hypothesis.