European journal of anaesthesiology
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Letter Comparative Study Clinical Trial
Measuring regional cerebral oxygen saturation during surgery in the prone position.
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Letter Case Reports
Xenon anaesthesia in a patient with susceptibility to malignant hyperthermia: A case report.
A case report describing the first-reported, successful and safe use of Xenon-based anesthesia in an MH-susceptible 31 year old male.
The authors conclude that this case, along with previous investigation of Xe in susceptible-swine animal models and in vitro human muscle biopsy testing, show that Xenon is likely safe for use in MH-susceptible individuals.
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Randomized Controlled Trial
Monitoring heart rate variability to assess experimentally induced pain using the analgesia nociception index: A randomised volunteer study.
Pain assessment using a numerical rating scale (NRS) is considered good clinical practice, but objective assessment in noncommunicating patients is still a challenge. A potential solution is to monitor changes in heart rate variability transformed into the analgesia nociception index (ANI), that offers a noninvasive means of pain quantification. ⋯ ANI did not allow a differentiation of painful, nonpainful or sham stimuli in alert volunteers. Therefore, ANI does not exclusively detect nociception, but may be modified by stress and emotion. Thus, we conclude that ANI is not a specific, robust measure for assessment of pain intensity.
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Letter Randomized Controlled Trial
Sevoflurane-induced reduction of bispectral index does not affect human cerebral microcirculation.