European journal of anaesthesiology
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Randomized Controlled Trial Multicenter Study
Goal-directed therapy during transthoracic oesophageal resection does not improve outcome: Randomised controlled trial.
Goal-directed therapy (GDT) is expected to be of highest benefit in high-risk surgery. Therefore, GDT is recommended during oesophageal resection, which carries a high risk of postoperative complications. ⋯ Goal-directed therapy during oesophageal resection did not result in a reduction of the incidence of postoperative complications.
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Multicenter Study Observational Study
Relevance of peripheral cholinesterase activity on postoperative delirium in adult surgical patients (CESARO): A prospective observational cohort study.
The cholinergic system is considered to play a key role in the development of postoperative delirium (POD), which is a common complication after surgery. ⋯ Peri-operative peripheral cholinesterase activities may be related to the development of POD, but the clinical implications remain unclear. Further studies, in homogeneous patient groups with a strict protocol for measurement time points, are needed to investigate the relationship between cholinesterase activities and POD.
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Comment Letter
Reply to: thromboprophylaxis in the obese surgical patient.