European journal of anaesthesiology
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Pectoral nerve blocks (PECS block) might be an interesting new regional anaesthetic technique in patients undergoing breast surgery. ⋯ CRD42019126733.
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Randomized Controlled Trial Multicenter Study
Efficacy of prehospital administration of fibrinogen concentrate in trauma patients bleeding or presumed to bleed (FIinTIC): A multicentre, double-blind, placebo-controlled, randomised pilot study.
Trauma-induced coagulopathy (TIC) substantially contributes to mortality in bleeding trauma patients. ⋯ Early fibrinogen concentrate administration is feasible in the complex and time-sensitive environment of prehospital trauma care. It protects against early fibrinogen depletion, and promotes rapid blood clot initiation and clot stability.
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Mortality among patients admitted to intensive care units (ICUs) with COVID-19 is unclear due to variable follow-up periods. Few nationwide data are available to compare risk factors, treatment and outcomes of COVID-19 patients after ICU admission. ⋯ Thirty-day mortality rate in COVID-19 patients admitted to Swedish ICUs is generally lower than previously reported despite a severe degree of hypoxaemia on admission. Mortality was driven by age, baseline disease severity, the presence and degree of organ failure, rather than pre-existing comorbidities.
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Randomized Controlled Trial
Effect of fluid resuscitation on cerebral integrity: A prospective randomised porcine study of haemorrhagic shock.
The treatment of haemorrhagic shock is a challenging task. Colloids have been regarded as standard treatment, but their safety and benefit have been the subject of controversial debates. Negative effects, including renal failure and increased mortality, have resulted in restrictions on their administration. The cerebral effects of different infusion regimens are largely unknown. ⋯ 23 177-07/G 15-1-092; 01/2016.
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Randomized Controlled Trial
Effects of magnesium on the dose of rocuronium for deep neuromuscular blockade: A randomised controlled trial.
Magnesium is known to enhance the effect of rocuronium, but the extent is not quantified. ⋯ Magnesium reduced the dose of rocuronium required for deep neuromuscular blockade by approximately 20% without affecting the recovery time after administration of sugammadex.