European journal of anaesthesiology
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Randomized Controlled Trial Meta Analysis Comparative Study
Remifentanil for labour analgesia: a meta-analysis of randomised controlled trials.
Remifentanil is a potent short-acting μ-opioid receptor agonist which is rapidly metabolised in the mother and fetus and may be ideal for labour analgesia. ⋯ During labour, remifentanil-PCA provided superior analgesia and higher patient satisfaction compared with pethidine with a comparable degree of adverse events. Epidural analgesia provided superior pain relief in comparison with remifentanil. Due to a low number of reported adverse events, the safety issue of remifentanil use in labour remains an open question that needs to be addressed in future trials.
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Randomized Controlled Trial Comparative Study
Comparison of the antiemetic effect of ramosetron and combined ramosetron and midazolam in children: a double-blind, randomised clinical trial.
Postoperative nausea and vomiting remains a clinically important problem after strabismus surgery in children. ⋯ Adding midazolam to ramosetron had no advantages over ramosetron alone in reducing the incidence of postoperative nausea and vomiting in children undergoing strabismus surgery.
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Randomized Controlled Trial Comparative Study
Subpleural block is less effective than thoracic epidural analgesia for post-thoracotomy pain: a randomised controlled study.
Thoracic epidural and paravertebral blocks provide adequate analgesia for postoperative thoracotomy pain. Both procedures are usually performed percutaneously with considerable failure rates. A subpleural catheter placed in the space posterior to the parietal pleura and alongside the paravertebral area may provide superior postoperative pain relief. ⋯ Thoracic epidural analgesia is superior to subpleural analgesia in relieving post-thoracotomy pain.
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The incidence of epidural haematoma after epidural anaesthesia is uncertain. ⋯ The incidence of spinal haematoma was 1: 6 628 in this general surgical population. When local anaesthetics are continuously applied, progressive motor block should increase the level of suspicion. When accompanied by pain or paraesthesia, progression to diagnosis by MRI is mandatory.