European journal of anaesthesiology
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Randomized Controlled Trial
The influence of residual neuromuscular block on the incidence of critical respiratory events. A randomised, prospective, placebo-controlled trial.
Post-operative residual paralysis is associated with a greater incidence of desaturation in the post-anaesthesia care unit.
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Randomized Controlled Trial Comparative Study
Myocardial oxidative stress protection by sevoflurane vs. propofol: a randomised controlled study in patients undergoing off-pump coronary artery bypass graft surgery.
Myocardial oxidative stress plays an essential role in the pathogenesis of ischaemia-reperfusion injury associated with coronary artery bypass grafting (CABG). Both propofol and volatile anaesthetics have been shown to reduce reactive oxygen species in experimental and clinical studies. ⋯ In patients undergoing off-pump CABG, sevoflurane showed better antioxidative properties than propofol.
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Comparative Study
Do intraoperative analgesics influence oncological outcomes after radical prostatectomy for prostate cancer?
The potential impact of intraoperative analgesics on oncological outcome after radical prostatectomy is debated. Some investigators have suggested that use of opioids favour relapse, whereas regional analgesia and NSAIDs improve oncological outcomes. ⋯ This retrospective analysis suggests that intraoperative sufentanil administration is associated with an increased risk of cancer relapse after RRP, whereas epidural analgesia, with local anaesthetic and opioid, was not associated with a significant effect.