European journal of anaesthesiology
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Comment Letter Case Reports
Masseter spasm after induction of general anaesthesia using propofol and remifentanil.
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Randomized Controlled Trial Comparative Study
Antiemetic efficacy of metoclopramide and diphenhydramine added to patient-controlled morphine analgesia: a randomised controlled trial.
the objective of this study was to assess whether antiemetic drugs metoclopramide and diphenhydramine, administered together as opposed to alone, can have better efficacy in preventing postoperative nausea and vomiting when added to patient-controlled morphine analgesia. ⋯ results of this study showed that a combination of metoclopramide with diphenhydramine in patients treated with dexamethasone at anaesthesia induction decreased postoperative nausea and vomiting compared to metoclopramide or diphenhydramine in these patients, when added to patient-controlled anaesthesia with morphine.
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Randomized Controlled Trial Comparative Study
Supplemental oxygen reduces serotonin levels in plasma and platelets during colorectal surgery and reduces postoperative nausea and vomiting.
it has been shown that supplemental oxygen reduces the incidence of postoperative nausea and vomiting (PONV) in patients undergoing colon surgery. Serotonin is a potent trigger of PONV. Theoretically, supplemental oxygen decreases gut ischaemia during surgery and in this way minimizes the release of serotonin. We investigated the release of serotonin during and after colorectal surgery with normal and supplemental oxygen administration. ⋯ an inspired oxygen fraction of 0.8 reduces serotonin levels significantly and decreases PONV significantly in patients undergoing colon surgery.
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Letter
Residual paralysis following a single dose of atracurium: results from a quality assurance trial.
Schreiber demonstrated a 27% incidence of PORC (Post-operative Residual Curarization/Paralysis = TOF ratio <0.9) after surgery between 60 and 90 minutes long.
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