Der Unfallchirurg
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The morbidity and mortality of polytrauma patients are substantially influenced by the extent of the posttraumatic inflammatory reaction. Studies have shown that TIMP‑1 and MMP‑9 play a major role in posttraumatic immune disorder in genome-wide mRNA microarray analyses. Furthermore, both showed differential gene expression profiles depending on the clinical parameters massive blood transfusion and traumatic brain injury. ⋯ Polytraumatized patients who received massive blood transfusions following major trauma showed significantly higher TIMP‑1 levels than patients who did not receive massive transfusions. This seems to be an expression of a massively excessive inflammatory reaction and therefore represents a substantial factor in the pathogenesis of severe posttraumatic immune dysfunction in this collective. Furthermore, the significant increase in MMP‑9 with accompanying traumatic brain injury reflects the pivotal role of matrix metalloproteinases in the pathophysiology of traumatic brain injury.
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The operative treatment of stiff shoulder using arthroscopically assisted arthrolysis is indicated in patients with persistent, symptomatic and therapy-resistant movement restrictions. Patients should be informed about relevant risks, supervised rehabilitation and possible recurrences. The surgical procedure provides a precise and controlled semicircular capsulotomy and is followed by an intensive rehabilitation program in order to minimize the risk of recurrences.
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The clinical examination of the knee joint represents a great challenge as well as a great opportunity. In particular, ligamentous injuries are understood better despite their complexity and thus treated in a more differentiated way. A purely radiologically based diagnosis is only possible to a limited extent, especially for chronic injuries. ⋯ This article gives an overview of the most important examination techniques of the knee joint, with which the decisive analysis of acute or chronic injuries and overuse syndromes of the knee can be carried out. Particularly in the field of ligament instability, this article provides a practical guide for the differentiated examination of complex rotational instability of the knee joint. In addition, the most important patellar and meniscal examination techniques are described.
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The γ‑nailing system is a widespread intramedullary therapeutic option that has been used for intertrochanteric and subtrochanteric fractures since the late 1980s; however, some reports from the 1990s describing femoral shaft fractures questioned the indications for this system in simple fracture types. Due to increasing numbers of patients treated with this system, the complication rate is continuously falling as confirmed by many recent studies. ⋯ The γ‑nailing system is a safe treatment option for trochanteric femoral fractures and failure of the implant is associated with high biomechanical forces in unstable fractures. A low complication rate is linked to a thorough surgical technique under consideration of a correct positioning of the implant.
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The influence of trauma-related kinematics on the injury pattern of the cervical spine is currently not considered in the available classification systems, only the force vector. Whether the strength of the trauma has an additional influence on the number and complexity of the injuries and whether this can be classified, has not yet been finally investigated. ⋯ Exact knowledge of the trauma mechanism is helpful in the primary treatment of an injured person. Injury patterns can be better estimated and the appropriate diagnostics can be initiated. The results underline the importance of immediate cervical spine immobilization even after minor trauma. In high velocity trauma, patients more often suffer from lower cervical spine injuries, especially C7. Due to the accumulation of multilevel spinal injuries in high velocity trauma, radiographic imaging of the whole spine is advisable.