Annals of Saudi medicine
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Annals of Saudi medicine · Mar 2014
Case ReportsCochlear implant for bilateral profound sensorineural hearing loss in an adolescent with sickle cell anemia.
We present the first-published cochlear implant in an adolescent with sickle cell anemia (SCA) and bilateral profound sensorineural hearing loss (SNHL). A 15-year-old Saudi girl, previously diagnosed with SCA, developed gradual bilateral permanent profound SNHL over 18 months and underwent a successful cochlear implantation. SNHL associated with sickle cell crises is a well-known phenomenon. Regular hearing assessments are recommended for sickle cell patients, and early referrals for cochlear implantations are advocated for those with permanent profound SNHL.
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Annals of Saudi medicine · Mar 2014
Multicenter Study Clinical TrialCorrelation of clinical efficacy and psychosocial impact on vitiligo patients by excimer laser treatment.
Vitiligo is a difficult disease to treat. Recently, a 308-nm excimer laser has been shown to be effective in treating vitiligo. In addition, the patients with vitiligo have impairment in their quality of life. The aim of the study was to investigate the clinical efficacy, safety, and psychosocial impact after treating vitiligo with the 308-nm excimer laser. ⋯ The clinical data indicate that the treatment of vitiligo using the 308-nm excimer laser is effective and safe and improves psychosocial quality of life. Lesion location, duration of disease, and treatment duration are factors affecting the clinical and psychological outcome.
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Annals of Saudi medicine · Mar 2014
Case ReportsCytoreductive surgery and hyperthermic intraperitoneal chemotherapy for managing peritoneal carcinomatosis from endometrial carcinoma: a single-center experience of 6 cases.
Endometrial carcinoma is the most common gynecologic malignancy worldwide. Prognosis of patients with peritoneal carcinomatosis (PC) from endometrial carcinoma is deadly, with an estimated median survival not exceeding 12 months. The objective of this study was to report our experience with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for managing PC from primary and recurrent endometrial carcinoma. ⋯ CRS and HIPEC are well-tolerated and feasibly promising management modalities in PC from primary and recurrent endometrial carcinoma. Further research is needed for in-depth analysis.
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Annals of Saudi medicine · Mar 2014
Case ReportsTranscatheter closure of residual postinfarction ventricular septal defect after dehiscence of surgical patch repair.
Ventricular septal defect (VSD) is a life-threatening complication of transmural myocardial infarction. Urgent surgical repair and concomitant revascularization are the standard of care. Percutaneous catheter-based closure techniques have been reserved for patients with a high-risk surgery or a failed surgical procedure with residual shunting. This case report demonstrates the successful transcatheter closure of residual VSD using the Amplatzer muscular VSD device (Amplatzer, Minnesota, USA) after surgical patch dehiscence for postinfarction VSD and 3-and-a-half years' post-intervention follow-up.
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Annals of Saudi medicine · Mar 2014
Visceral leishmaniasis-hepatitis B/C coinfections: a rising necessity to triage patients for treatment.
Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In Sudan, VL is caused by L donovani. Most drugs used to treat VL, especially pentavalent antimony compounds (sodium stibogluconate, SSG), are potentially hepatotoxic. A number of fatal catastrophes happened because patients with VL-hepatitis B/C coinfection were indiscriminately treated with SSG in settings where VL and viral hepatitis coexist. This study aimed to study biochemical and hematological parameters of patients with VL-hepatitis B/C coinfections with the aim to modify treatment protocols to reduce coinfection.added morbidity and mortality. ⋯ VL-hepatitis B/C coinfections are an emerging entity that needs anti-leishmanial treatment modification. Alternative treatments like paromomycin and amphotericin B (AmBisome) could be reserved for these patients.