Anaesthesia and intensive care
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A prospective survey of one thousand and sixty-two patients receiving epidural analgesia in surgical wards was undertaken over a two-year period. The duration of infusion ranged from one to fourteen days, with a mode of three days. There were 1131 episodes where a local anaesthetic and opioid mixture was used and 160 where opioids were used alone. ⋯ Epidural analgesia can be used safely in surgical wards provided that regular review of the patients is undertaken. It must be anticipated however, that up to 20% of patients will not receive adequate analgesia for the first 48 hours postoperatively. The failure rate could be halved if accidental dislodgement of epidural catheters could be eliminated.
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Anaesth Intensive Care · Apr 1998
Case ReportsRemifentanil and propofol total intravenous anaesthesia for thymectomy in myasthenia gravis.
We report a case of trans-sternal thymectomy for myasthenia gravis using a non relaxant, total intravenous technique with propofol and remifentanil. This afforded excellent control of heart rate and pressor responses during surgery while allowing early return of spontaneous ventilation and extubation within nine minutes of termination of anaesthesia. Advantages and disadvantages of this approach versus relaxant and volatile techniques are discussed with particular reference to preservation of neuromuscular function.
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Anaesth Intensive Care · Apr 1998
Case ReportsOxygen contamination of the nitrous oxide pipeline supply.
Midogas (CIG Australia) nitrous oxide/oxygen blenders are commonly used in delivery wards in Australia. In this case report we describe an incident where a small hole in the diaphragm of the oxygen failure alarm in a Midogas nitrous oxide/oxygen blender led to retrograde flow of oxygen contaminating the nitrous oxide pipeline supply to the operating theatres and the delivery ward. ⋯ However, if the oxygen pipeline pressure had been lower than the nitrous oxide pipeline pressure, the contamination would have been reversed, potentially resulting in a hypoxic mixture being delivered to many patients. Suggestions are made as to a method of prevention of this problem.
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Anaesth Intensive Care · Apr 1998
Comparative StudyAnaesthesia circuits, humidity output, and mucociliary structure and function.
We compared the effects of humidity delivered by the circle system at low fresh gas flows (FGF) with a conventional two-limb and coaxial circuit on the structure and function of the tracheobronchial epithelium in dogs. Animals were anaesthetized and mechanically ventilated using an anaesthesia ventilator to maintain normocarbia. Group I (control) animals received a FGF equal to the required minute ventilation mimicking an open circuit technique. ⋯ Alterations in tracheobronchial structure and function result from exposure to dry gases and are amplified by the duration of exposure. Our findings suggest a minimum of 12 to 15 mg H2O/l is necessary to prevent these alterations. In this study, the combination of low FGF and a coaxial anaesthesia circuit reached this minimum threshold more quickly than a conventional two-limb circuit.
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Anaesth Intensive Care · Apr 1998
Case ReportsCentral nervous system toxicity attributable to epidural ropivacaine hydrochloride.
Ropivacaine, a new local anaesthetic agent, has been demonstrated to have less potential than bupivacaine for central nervous system toxicity on the basis of human and animal studies. We report a case of a convulsion secondary to presumed inadvertent intravascular injection of 20 mg of ropivacaine in a 44 kg patient during an epidural for chronic pain. There were minimal signs of cardiovascular toxicity.