Anaesthesia and intensive care
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Anaesth Intensive Care · Sep 2010
Continuous central venous oxygen saturation monitoring under varying physiological conditions in an animal model.
We compared saturations from a paediatric central venous oximetry catheter with co-oximetry values with changes in drug infusions, intravascular blood volume and hypoxia in an animal model. Piglets (large white) were anaesthetised, intubated and mechanically ventilated. PediaSat oximetry catheters were placed in the superior vena cava via jugular vein cut-down and in the inferior vena cava percutaneously via the femoral vein. ⋯ During the hypoxia study there was good agreement between the co-oximeter to ScvO2-superior catheter but poor agreement with to the inferior vena cava catheter samples. In the hypovolaemic phase of the experiment there was good agreement between the measured co-oximetry value and ScvO2-superior catheter until the mean blood pressure reached 43 mmHg. The oximetry catheter is capable of identifying changes in ScvO2 under physiological conditions usually encountered in clinical medicine but was less accurate at the extremes of physiology and when placed in the inferior vena cava catheter especially during hypovolaemia and hypoxia.
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Anaesth Intensive Care · Sep 2010
Estimating the net effect of unmeasured ions in human extracellular fluid using a new mathematical model. Part I: Theoretical considerations.
A theoretical framework for the formulation of a derived variable to be used for the prediction of the net effect of unmeasured charged species present in human extracellular fluid was explored. This new variable was based on contemporary strong ion and classical buffer base theories and tested against the standard base excess using simulation. It proved to be more accurate in predicting the existence of unmeasured charged species in the extracellular fluid when disturbances of either strong ions, weak acids or both were present.
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Anaesth Intensive Care · Sep 2010
Anaesthesia-related morbidity in Victoria: a report from 1990 to 2005.
This report involves a review of 736 cases of anaesthesia-related morbidity reported from 1990 to 2005 by the Victorian Consultative Council on Anaesthetic Mortality and Morbidity. Using a combination of an established classification system, emerging categorisation definitions and appropriate keywords, an analysis of the clinical issues and contributory factors was undertaken. Airway-related morbidity, respiratory complications and drug-related adverse events are the most commonly reported. Organisational issues are increasingly implicated in adverse anaesthesia outcomes.
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Anaesth Intensive Care · Sep 2010
Letter Case ReportsRocuronium and sugammadex in myotonic dystrophy.
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Anaesth Intensive Care · Sep 2010
Comment Historical ArticleThe history of depth of anaesthesia monitoring.