Anaesthesia and intensive care
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Anaesth Intensive Care · Jan 2011
Speeding dantrolene preparation for treating malignant hyperthermia.
Dantrolene is known to have a low solubility in water Studies have demonstrated that it dissolves more rapidly in warm water However, the overall benefit of warming has not been measured. This study evaluated the overall time benefit of warming. The first step was to measure how long it took to warm the 10 ml plastic ampoules of sterile water from ambient temperature (20 degrees C) to 45 degrees C. ⋯ Thus the time difference in preparation was about 256 seconds, which is the time that could be saved in preparing the standard dose of 10 vials of dantrolene using water at 45 degrees C. However, as it required about seven minutes to initially warm the sterile ampoules, there would be a net increase, not decrease in the time required. These findings indicate that warming is of no benefit in speeding dantrolene preparation.
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Anaesth Intensive Care · Jan 2011
Biography Historical ArticlePituri and other Aboriginal medicines for pain relief.
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Anaesth Intensive Care · Jan 2011
Letter Case ReportsThe i-gel in failed obstetric tracheal intubation.