Anaesthesia and intensive care
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Anaesth Intensive Care · Feb 1993
Biography Historical ArticleCattlin's bag and Clover's facepiece for nitrous oxide anaesthesia.
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Anaesth Intensive Care · Nov 1992
Randomized Controlled Trial Comparative Study Clinical TrialThe effect of epidural blockade on postoperative hypercoagulability following abdominal aortic bypass surgery.
The effect of epidural blockade on postoperative hypercoagulability was assessed in patients undergoing elective abdominal aortic bypass surgery. Twenty patients were randomised to receive general anaesthesia alone, or general anaesthesia plus thoracic epidural blockade with 0.5% bupivacaine. ⋯ Similarly, epidural blockade did not affect the postoperative decrease in antithrombin III. The results suggest that epidural blockade with local anaesthetic agents does not prevent the postoperative hypercoagulability response following abdominal aortic bypass surgery.
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Anaesth Intensive Care · Nov 1992
Randomized Controlled Trial Clinical TrialPropofol induction for laryngeal mask airway insertion: dose requirement and cardiorespiratory effects.
The dosage, haemodynamic and respiratory effects of propofol for laryngeal mask airway (LMA) insertion were investigated. Fifty patients (ASA I-II) were randomly assigned one of four induction doses of propofol (1.5-2.5 mg/kg) delivered over 30 seconds and the first attempt at LMA insertion was made at 90 seconds. The LMA was inserted at 90 seconds in 35 patients and by 300 seconds in 13 others (mean plasma concentration at 90 seconds was 7.7 mcg/ml (no delay) versus 5.2 mcg/ml (insertion delayed), P < 0.01). ⋯ Additional propofol (0.5 mg/kg/30s) was required in 22 patients for LMA insertion or to prevent movement, resulting in propofol concentrations at 120-180 seconds above 7 mcg/ml. Respiratory effects were minor, but MAP decreased by 18 +/- 1.4 mmHg at 90 seconds. Cardiovascular effects did not differ significantly between dosage groups or with the use of additional propofol.