The Clinical journal of pain
-
Randomized Controlled Trial Comparative Study
Consistent management of repeated procedural pain with sucrose in preterm neonates: Is it effective and safe for repeated use over time?
Preterm neonates undergo numerous painful procedures in the neonatal intensive care unit (NICU). Sucrose, with and without pacifiers, is effective and safe for relieving pain from single painful events. However, repeated use of sucrose for multiple painful procedures has not been adequately evaluated. The study objectives were to: 1) determine the efficacy and safety of consistent management of repeated procedural pain with sucrose; and 2) explore the impact of consistent pain management on clinical outcomes and neurobiological risk status. ⋯ Consistent management of painful procedures with sucrose plus pacifier was effective and safe for preterm neonates during their stay in the NICU. Further exploration of consistent pain management with sucrose on clinical, developmental, and neurobiological outcomes is required.
-
Comparative Study
Stressful experiences in childhood and chronic back pain in the general population.
To determine if stressful experiences in childhood are associated with an increased risk of chronic back problems later in life. ⋯ Our study shows that persons reporting multiple stressful experiences in childhood are at increased risk of developing chronic back problems.
-
Comparative Study
Age and the experience of chronic pain: differences in health and quality of life among younger, middle-aged, and older adults.
To describe age differences in chronic pain and to evaluate for differences in demographic and health-related variables among younger (18-39 years), middle-aged (40-59 years), and older adults (60-81 years) who reported chronic pain. ⋯ This study found that the prevalence rates for chronic pain do vary with age and that the middle-aged group may be a high-risk group of patients with chronic pain.
-
Comparative Study
Procedural distress in children with cancer: self-report, behavioral observations, and physiological parameters.
To examine the relationship among different indicators of pain and distress, including self-report, behavioral observations, and physiological parameters, in children with cancer undergoing invasive procedures. ⋯ Self-report measures, behavioral indicators, and physiological changes are not interchangeable outcomes. Treatment strategies were effective for minimizing subjective and behavioral distress, but not necessarily for physiological reactions. Future research should focus on individual differences in these responses, and treatment outcome studies aimed at reducing distress must be clear about the specific goals of intervention.
-
Case Reports
Effectiveness of pamidronate for treating intractable chronic neuropathic pain: case report of two adolescents.
The objective of this study is to evaluate the effectiveness of pamidronate for the treatment of chronic neuropathic pain refractory to previous management. Intravenous pamidronate (60 mg/day for 3 days) was administered to 2 adolescents with neuropathic pain refractory to previous multidisciplinary treatments. Pain intensity, functional improvement, and adverse effects were evaluated. ⋯ In contrast to recent positive reports in adults, pamidronate was not effective in decreasing pain or improving function in 2 adolescents with chronic neuropathic pain. Pamidronate may be effective only when pain is accompanied by abnormal bone density. Future trials should include scans to document bone density pretherapy and posttherapy.