The Clinical journal of pain
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Comparative Study
Stressful experiences in childhood and chronic back pain in the general population.
To determine if stressful experiences in childhood are associated with an increased risk of chronic back problems later in life. ⋯ Our study shows that persons reporting multiple stressful experiences in childhood are at increased risk of developing chronic back problems.
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Comparative Study
Age and the experience of chronic pain: differences in health and quality of life among younger, middle-aged, and older adults.
To describe age differences in chronic pain and to evaluate for differences in demographic and health-related variables among younger (18-39 years), middle-aged (40-59 years), and older adults (60-81 years) who reported chronic pain. ⋯ This study found that the prevalence rates for chronic pain do vary with age and that the middle-aged group may be a high-risk group of patients with chronic pain.
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Case Reports
Effectiveness of pamidronate for treating intractable chronic neuropathic pain: case report of two adolescents.
The objective of this study is to evaluate the effectiveness of pamidronate for the treatment of chronic neuropathic pain refractory to previous management. Intravenous pamidronate (60 mg/day for 3 days) was administered to 2 adolescents with neuropathic pain refractory to previous multidisciplinary treatments. Pain intensity, functional improvement, and adverse effects were evaluated. ⋯ In contrast to recent positive reports in adults, pamidronate was not effective in decreasing pain or improving function in 2 adolescents with chronic neuropathic pain. Pamidronate may be effective only when pain is accompanied by abnormal bone density. Future trials should include scans to document bone density pretherapy and posttherapy.