The Clinical journal of pain
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Randomized Controlled Trial Comparative Study
A comparison of migraine patients with and without allodynic symptoms.
Although the association of symptoms of allodynia with migraine have been reported, there is a paucity of studies on Asians. ⋯ Allodynic symptoms occurred in 57.1% patients with migraine. In allodynic patients with moderate-to-severe headache, rizatriptan resulted in greater pain relief compared with ibuprofen. These results need further confirmation in larger study.
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Determine the impact of co-occurring chronic pain and obesity on health-related quality of life (HRQOL) in children and adolescents. ⋯ Co-occurring chronic pain and obesity exacerbates the impact of chronic pain alone on the HRQOL of children and adolescents. Routinely screening pediatric patients with chronic pain for elevated body mass index is recommended.
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Randomized Controlled Trial Comparative Study
Lidocaine-based topical anesthetic with disinfectant (LidoDin) versus EMLA for venipuncture: a randomized controlled trial.
To examine the efficacy and safety of a new topical anesthetic containing a disinfection ingredient (LidoDin cream) in reducing the pain associated with venipuncture by comparing it with the proven eutectic mixture of lidocaine 2.5% and prilocaine 2.5% (EMLA cream). ⋯ This pilot study demonstrated that LidoDin and EMLA seem to be equally safe and effective topical anesthetics for venipuncture. Future studies are planned to determine, if LidoDin reduces the rate of local skin infection in patients treated with multiple daily subcutaneous injections of medications.
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Randomized Controlled Trial
Transcranial DC stimulation coupled with TENS for the treatment of chronic pain: a preliminary study.
Based on evidence showing that electrical stimulation of the nervous system is an effective method to decrease chronic neurogenic pain, we aimed to investigate whether the combination of 2 methods of electrical stimulation-a method of peripheral stimulation [transcutaneous electrical nerve stimulation (TENS)] and a method of noninvasive brain stimulation [transcranial direct current stimulation (tDCS)]-induces greater pain reduction as compared with tDCS alone and sham stimulation. ⋯ The results of this pilot study suggest that the combination of TENS with tDCS has a superior effect compared with tDCS alone.