The Clinical journal of pain
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Patients with an implanted spinal cord stimulation (SCS) system for pain management present an opportunity to study dynamic changes in the pain system in a situation where patients are not stimulated (ie, experiencing severe pain) compared with a situation in which patients have just been stimulated (ie, pain free or greatly reduced pain). The aims of this study were (1) to determine if there are differences in nociceptive withdrawal reflex thresholds (NWR-T) and electrical pain thresholds (EP-T) before and after SCS; and (2) to establish if these differences are related to psychological factors associated with chronic pain. ⋯ The results of this study suggest that pain relief after SCS is partially mediated by a decrease in the excitability of dorsal horn neurons in the spinal cord.
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To characterize the incidence, severity, quality, and treatment of pain in a large cohort of Marfan patients. ⋯ Our findings suggest that pain symptoms in Marfan patients are underestimated and likely undertreated. We propose a need for improved patient and medical provider awareness of pain management options in this population, including the development of effective algorithms to treat pain in Marfan patients.
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To test the hypothesized associations between measures of the behavioral inhibition system (BIS) and behavioral activation system (BAS) and both the intensity and frequency of pain. ⋯ The findings are consistent with predictions based on a model hypothesizing that pain has a nonlinear impact on both BIS and BAS, with a stronger impact on BIS than BAS. If the current results are replicated in other samples, including samples of individuals with chronic pain, they have important implications for identifying biological factors that could influence pain and behavioral responses to pain, as well as for the development and evaluation of treatments that could enhance positive treatment outcomes.
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The objectives of this study: (1) to assess whether Multidimensional Pain Inventory (MPI) profiles predicted differential responses to a functional restoration program (FRP) in chronic disabling occupational musculoskeletal disorder (CDOMD) patients; (2) to examine whether coping style improves following FRP; and (3) to determine whether discharge MPI profiles predict discharge psychosocial and 1-year socioeconomic outcomes. ⋯ An FRP was clinically effective for CDOMD patients regardless of initial MPI profiles. The FRP modified profiles, with patients changing from negative to positive profiles. Discharge DYS were more likely to have poor 1-year outcomes. Those classified as Anomalous had a good prognosis for functional recovery similar to ACs.