Ophthalmic plastic and reconstructive surgery
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Ophthal Plast Reconstr Surg · Jan 2007
Case ReportsNewly recognized ocular side effects of erlotinib.
An 85-year-old man had a bilateral periorbital rash and conjunctivitis leading to lower eyelid ectropion and epiphora within 6 weeks of treatment with erlotinib (Tarceva, Genentech, Inc., San Francisco, CA, and OSI Pharmaceuticals, Melville, NY), a second-line antineoplastic agent. The treatment was discontinued secondary to toxicity, and the periorbital rash completely resolved within 6 weeks of cessation of the drug. To our knowledge, the periorbital rash resulting in bilateral lower eyelid ectropion associated with epiphora is a newly recognized side effect of erlotinib that is completely reversible with discontinuation of the drug. The rash and ectropion should be treated palliatively, and surgical intervention should be avoided unless the patient cannot be removed from treatment.
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Ophthal Plast Reconstr Surg · Jan 2007
Long-term follow-up of porous polyethylene spherical implants after enucleation and evisceration.
To present long-term follow-up data on enucleations and eviscerations carried out with placement of spherical porous polyethylene implants. ⋯ Our case series revealed a significantly higher incidence of implant exposure after evisceration than after enucleation. Our data suggest that enucleation should be the procedure of choice when removing an eye to minimize the risk of subsequent complications, particularly orbital implant exposure.
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Ophthal Plast Reconstr Surg · Jan 2007
Comparative StudyUse of a novel topical hemostatic sealant in lacrimal surgery: a prospective, comparative study.
FloSeal Matrix is a new, two-component (collagen granules and thrombin), topical hemostatic sealant. We prospectively evaluated the role of FloSeal Matrix in achieving hemostasis in dacryocystorhinostomy (DCR) surgery and its intraoperative characteristics (ease of use). We hypothesize that FloSeal will efficiently control bleeding in patients and eliminate the need for postoperative intranasal dressing. ⋯ FloSeal Matrix is an effective hemostasis adjunct in patients undergoing lacrimal surgery. It has the added benefits of high patient satisfaction and ease of use.
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To ensure the MRI compatibility of various eyelid implants in high-field MRI, 3 eyelid weights made of pure gold (99.99%), pure platinum (99.95%), and a platinum (97%)/iridium (3%) alloy were examined in vitro. Temperature changes, position changes, and imaging artifacts of the different implants were determined in a small-bore 7.0 Tesla MRI system. The 7.0 Tesla MRI system demonstrated that none of the eyelid implants carried a risk of heating or dislocation; therefore, these implants are MRI compatible up to a magnetic field strength of 7.0 Tesla.
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Ophthal Plast Reconstr Surg · Sep 2006
Case ReportsJuvenile dermatomyositis presenting with periorbital edema.
Juvenile dermatomyositis is a rare disease that affects the skin and muscles. It often presents with a classic heliotrope eyelid rash. We present a case of juvenile dermatomyositis presenting with significant bilateral periorbital edema, with its complete resolution after systemic antiinflammatory therapy.