Journal of general internal medicine
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Data suggest that there were disparities in H1N1 vaccine uptake, and these may inform COVID-19 vaccination efforts. We conducted a systematic review to evaluate disparities in H1N1 vaccine uptake, factors contributing to disparities, and interventions to reduce them. ⋯ PROSPERO CRD42020187078.
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Anticholinergic medications may increase risk of dementia and stroke, but prospective studies in healthy older people are lacking. ⋯ High anticholinergic burden in initially healthy older people was associated with increased risk of incident dementia and ischemic stroke. A vascular effect may underlie this association. These findings highlight the importance of minimizing anticholinergic exposure in healthy older people.