Journal of pain and symptom management
-
J Pain Symptom Manage · Jul 2013
Restless legs syndrome as a cause of sleep disturbances in cancer patients receiving chemotherapy.
Sleep disturbances are frequent in cancer patients during chemotherapy; the contributory role of restless legs syndrome (RLS) in this setting has never been assessed. ⋯ RLS can be a contributory factor in sleep disturbances in cancer patients undergoing chemotherapy. Screening for RLS could aid in tailoring a potentially more efficacious treatment of such disturbances.
-
The use of targeted therapy at the end of life has not been well characterized. ⋯ Targeted agents were used as often as chemotherapy at the end of life, particularly among younger patients and those with hematologic malignancies. Guidelines on targeted therapy use at the end of life are needed.
-
J Pain Symptom Manage · Jul 2013
Alteration in pain modulation in women with persistent pain after lumpectomy: influence of catastrophizing.
Persistent pain is common after surgical treatment of breast cancer, but fairly little is known about the changes in sensory processing that accompany such pain syndromes. ⋯ These findings suggest that persistent postoperative pain is associated with alterations in central nervous system pain-modulatory processes. Future treatment studies might benefit from targeting these pain-modulatory systems, and additional studies using functional neuroimaging methods might provide further valuable information about the pathophysiology of long-term postsurgical pain in women treated for breast cancer.
-
J Pain Symptom Manage · Jul 2013
Long-term control of refractory hemorrhagic radiation proctitis with ozone therapy.
Persistent or severe hemorrhagic radiation proctitis (HRP) has limited therapeutic options. ⋯ Persistent advanced HRP was significantly improved with O3T. The addition of O3T can be useful as a complementary treatment in the long-term management of HRP and, as such, merits further evaluation.