The Laryngoscope
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Dysphonia due to vocal fold scarring is a challenging problem to the laryngologist. Vocal fold scarring after radiation, phonosurgery, and laser cordectomy causes moderate to severe dysphonia. Surgical attempts at scar removal and voice restoration have limited success. Pulsed dye laser (PDL) treatment has been shown to be effective in softening scarred skin by serial office treatments. The objective of this preliminary study was to evaluate the use of the PDL in the management of patients with established vocal fold scar. ⋯ PDL is a safe and potentially promising treatment for established vocal fold scar. Subjectively, no patients were worse and 10 of 11 patients reported improved voice. There was improvement in the VHI, acoustic measures of shimmer and jitter, and stroboscopy findings. Further study using this approach in a larger cohort seems to be warranted.
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Randomized Controlled Trial Comparative Study
Tramadol for pain relief in children undergoing adenotonsillectomy: a comparison with dextromethorphan.
Establishment of good analgesia is of major concern in the postoperative period after adenotonsillectomy. The aim of this study was to compare the effects of dextromethorphan and tramadol on postoperative pain after adenotonsillectomy in children. ⋯ Intravenous tramadol (1 mg/kg) is more suitable than 1 mg/kg dose of dextromethorphan cough syrup oral in reducing posttonsillectomy pain in children.
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Randomized Controlled Trial Comparative Study
Multiple analyses of factors related to intraoperative blood loss and the role of reverse Trendelenburg position in endoscopic sinus surgery.
To find out the factors related to the volume of intraoperative blood loss during endoscopic sinus surgery and to validate the role of reverse Trendelenburg position (RTP) in controlling blood loss. ⋯ RTP may reduce intraoperative blood loss. Besides, fungal sinusitis and rhinosinusitis without polyposis may contribute to a lesser intraoperative blood loss.
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Randomized Controlled Trial
Efficacy of sinonasal simulator in teaching endoscopic nasal skills.
To develop a nasal model (NM) which accurately simulates human texture and anatomy and to study the effect of training with NM on performance of video rigid nasal endoscopy and video flexible laryngoscopy. At the conclusion of this presentation, the participants should be able to demonstrate that training with nasal endoscopic simulation enhances efficiency and may improve comfort to the patient. ⋯ Our NM accurately simulates human texture and anatomy and provides an opportunity for endoscopic training without concern of bloodborne pathogens and expense of cadavers. Further development of the NM is warranted to expand the training utility.
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Gentamicin application is an important therapeutic option for Ménière's disease. However, even if given at intervals, a destruction of the cochlea was often observed in various animal models together with an increased content of nitric oxide (NO) and reactive oxygen species. The present study was undertaken to identify the correlation between hearing threshold alteration and the NO production in the lateral wall and organ of Corti of the guinea pig in response to gentamicin application. ⋯ The correlation between hearing threshold shift and NO production in the cochlea leads to the assumption that increased NO contributes to gentamicin-induced hearing impairment.