The Laryngoscope
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To evaluate and discuss the role of acellular human dermal matrix (AlloDerm, LifeCell Corp., Branchburg, NJ) graft for coverage of radial forearm free flap donor site. ⋯ AlloDerm graft is a viable alternative to split-thickness skin graft for coverage of the radial forearm free flap donor site.
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Comparative Study
Histopathology of the uvula and the soft palate in patients with mild, moderate, and severe obstructive sleep apnea.
To study morphometric and qualitative histopathologic changes of the soft palate and uvula in patients with mild, moderate, and severe obstructive sleep apnea. ⋯ The structure of the distal soft palate and uvula of patients with obstructive sleep apnea undergoes insignificant changes and is independent of the body mass index levels, indicating that the pathologic changes are probably the sequela of airway obstruction rather than its cause.
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Randomized Controlled Trial Comparative Study Clinical Trial
Efficacy of single-dose dexamethasone as adjuvant therapy for acute pharyngitis.
Pharyngeal inflammatory pain is reduced by a single dose of dexamethasone. ⋯ Single-dose dexamethasone appears to be a safe, effective, and inexpensive adjunctive treatment for acute pharyngitis in patients 15 years of age and older. Patients treated with intramuscular or oral dexamethasone had significant relief of pain (relative to baseline) compared with patients who were given placebo. Identification of a bacterial pathogen had a significant impact on the response to dexamethasone.
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Comparative Study Clinical Trial Controlled Clinical Trial
Recovery after tonsillectomy in adults: a three-week follow-up study.
To evaluate recovery after tonsillectomy and safety and efficacy of ketoprofen in pain treatment after discharge. ⋯ The main problem after tonsillectomy is significant pain that can last 11 to 12 days after surgery. Ketoprofen combined with paracetamol-codeine provided sufficient analgesia for most patients at home, but because ketoprofen may cause an increase in the secondary hemorrhage rate, it should be prescribed with caution.
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Sentinel lymph node biopsy has been introduced for head and neck cancer with promising results. Research in breast cancer has revealed different histopathological features of occult lymph node metastasis with possibly different clinical and prognostic implications. The aim of the study was to evaluate the histopathological features of occult metastasis detected by sentinel lymph node in oral and oropharyngeal squamous cell carcinoma. ⋯ Occult metastasis can be subdivided histopathologically in isolated tumor cells, micrometastasis, and macrometastasis. We present the first study describing a great variety of these subtypes in sentinel lymph nodes from head and neck squamous cell carcinoma. Because the independent prognostic factor and clinical relevance of these subtypes is still unclear, we emphasize the importance of reporting these findings uniformly and according to well-established criteria.