International journal of colorectal disease
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Int J Colorectal Dis · Apr 2016
Using CRP to predict anastomotic leakage after open and laparoscopic colorectal surgery: is there a difference?
C-reactive protein (CRP) has proven to be a useful adjunct in early diagnosis of anastomotic leak (AL) after colorectal surgery. It would be of considerable value to examine whether modality of surgery has influence upon postoperative CRP serum levels and their predictive value in the diagnosis of AL. ⋯ CRP levels are higher after open surgery compared with laparoscopic surgery, both with and without AL. AL generates a significant detectable increase in CRP within 2-4 days after surgery.
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Int J Colorectal Dis · Apr 2016
Factors associated with the location of local rectal cancer recurrence and predictors of survival.
The location of locally recurrent rectal cancer (LRRC) may influence survival. This study examines factors affecting the location of LRRC, the effect of LRRC location on survival, and predictive factors for survival in patients with LRRC. ⋯ The current study suggests that features of the primary tumour and technical factors at the time of index proctectomy influence both the location of LRRC and survival.
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Int J Colorectal Dis · Apr 2016
Malnutrition in rectal cancer patients receiving preoperative chemoradiotherapy is common and associated with treatment tolerability and anastomotic leakage.
This study assessed the incidence of malnutrition caused by preoperative chemoradiotherapy (CRT) in rectal cancer patients, which is seemingly underestimated; however, malnutrition affects treatment tolerability, postoperative complications, including anastomotic leakage (AL), and oncological outcomes. ⋯ Malnutrition caused by CRT is common and is associated with treatment tolerability and AL. Nutritional assessment and support seem indispensable for the rectal cancer patients receiving CRT.
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Int J Colorectal Dis · Mar 2016
Multicenter Study Observational StudyFerric carboxymaltose reduces transfusions and hospital stay in patients with colon cancer and anemia.
The purpose of the study was to evaluate the efficacy of preoperative intravenous (IV) ferric carboxymaltose (FCM) administration vs. no-IV iron in colon cancer (CC) anemic patients undergoing elective surgery with curative intention. ⋯ Preoperative ferric carboxymaltose treatment in patients with CC and iron deficiency anemia significantly reduced RBC transfusion requirements and hospital length of stay, reaching higher response rates and percentages of normalized hemoglobin levels both at hospital admission and 30 days post-surgery.
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Int J Colorectal Dis · Mar 2016
Current use of diverting stoma in anterior resection for cancer: population-based cohort study of total and partial mesorectal excision.
A diverting stoma is commonly used to reduce the risk of anastomotic leakage when performing total mesorectal excision (TME) in anterior resection for rectal cancer. The purpose of this study was to evaluate the impact of fecal diversion in relation to partial mesorectal excision (PME). ⋯ The benefit of a diverting stoma concerning anastomotic leakage in this patient group seems doubtful. Moreover, the diverting stoma itself may contribute to the high rate of permanent stomas.