Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Feb 2016
Effects of esophageal capsaicin instillation on acid induced excitation of secondary peristalsis in humans.
Esophageal instillation of capsaicin or hydrochloric acid enhances secondary peristalsis. Our aim was to investigate whether intra-esophageal capsaicin infusion can influence symptom perception and physiological alteration of secondary peristalsis subsequent to acid infusion. ⋯ Capsaicin appears to desensitize the esophagus to acid induced excitation of secondary peristalsis in humans, which is probably mediated by rapidly adapting mucosal mechanoreceptors. High capsaicin-containing diet might attenuate normal physiological response to abrupt acid reflux by inhibiting secondary peristalsis.
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J. Gastroenterol. Hepatol. · Jan 2016
Randomized Controlled Trial Comparative StudyNaso-jejunal fluid resuscitation in predicted severe acute pancreatitis: Randomized comparative study with intravenous Ringer's lactate.
Early management of severe acute pancreatitis (SAP) includes intravenous fluid resuscitation. ⋯ In select group of patients with SAP, NJ fluid resuscitation with ORS is feasible and is equally efficacious as IV fluid resuscitation with RL.
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J. Gastroenterol. Hepatol. · Jan 2016
Multicenter Study Comparative StudyComparison of scoring systems for nonvariceal upper gastrointestinal bleeding: a multicenter prospective cohort study.
The Glasgow-Blatchford score (GBS) and Rockall score (RS) are widely used to assess risk in patients with upper gastrointestinal bleeding (UGIB). We compared both scoring systems and evaluated their clinical usefulness. ⋯ cris.nih.go.kr/KCT0000514).
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J. Gastroenterol. Hepatol. · Jan 2016
Top-cited articles in digestive system disease from 1950 to 2013.
Examination of top-cited articles is a tool that can help to identify and monitor outstanding scientific researches and landmark papers. We aimed to identify the 100 most cited published papers in peer-reviewed biomedical journals in the field of digestive diseases and to examine their characteristics. ⋯ Our study can give a historical perspective on the scientific progress of digestive diseases, as well as allow for recognition of most important advances in this area and provide useful information to guide future researches.
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J. Gastroenterol. Hepatol. · Nov 2015
Ameliorating effects and autonomic mechanisms of needle-less transcutaneous electrical stimulation at ST36 on stress-induced impairment in gastric slow waves.
Stress has long been documented to alter gastrointestinal motility. The effects of electroacupuncture (EA) on stress and gastric motility are relatively well known; however, whether EA has an ameliorating effect on stress-induced dysmotility remained unclear. This study aims to investigate the effects and mechanisms of needle-less transcutaneous electroacupuncture (TEA) on stress-induced impairment in gastric slow waves. ⋯ Needle-less TEA at ST36 using a watch-size stimulator is able to improve stress-induced impairment in gastric slow waves, possibly mediated via the autonomic mechanism. Home-based needle-less TEA may be a viable therapy for stress-induced impairment in gastric motility functions.