Journal of gastroenterology and hepatology
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J. Gastroenterol. Hepatol. · Jul 2008
Elevation of pentylenetetrazole-induced seizure threshold in cholestatic mice: interaction between opioid and cannabinoid systems.
Several studies have reported that endogenous opioid and cannabinoid systems may be involved in some pathophysiological changes occurring in cholestatic liver disease. It is well known that endogenous opioids and cannabinoids alter the susceptibility of experimental animals to different models of seizure. ⋯ Both opioid and cannabinoid CB(1) receptors may be involved in the dramatic increase in pentylenetetrazole-induced seizure threshold in cholestasis.
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J. Gastroenterol. Hepatol. · Jun 2008
Editorial Comment ReviewVAT fat is bad for the liver, SAT fat is not!
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Although numerous studies have evaluated outcomes pertaining to endoscopic retrograde cholangio-pancreatography (ERCP) complications, studies evaluating outcomes of management of post-ERCP pancreatitis are scant. This study evaluated the effectiveness of a standard treatment protocol in management of post-ERCP pancreatitis. ⋯ A protocol-based management strategy was associated with less severe pancreatitis, shorter length of hospital stay, need for fewer imaging studies, and use of antibiotics. Prospective validation of these findings is justified.
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J. Gastroenterol. Hepatol. · Mar 2008
ReviewScientific publications in gastroenterology and hepatology journals from Chinese authors in various parts of North Asia: 10-year survey of literature.
People of Chinese ethnicity are one of the groups at most risk of gastrointestinal and liver diseases in the world. The research status in gastroenterology and hepatology (gastrointestinal [GI]) among Chinese individuals in the three major regions of China-the mainland (ML), Hong Kong (HK), and Taiwan (TW)-are unknown. The outputs of articles published in international GI journals from the three regions were compared in this study. ⋯ The difference between the number of GI research articles published in the ML, TW, and HK still appears to be considerable, particularly when assessed by IF, although the gap appears to be narrowing.