Revista clínica española
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Revista clínica española · Nov 1989
[2,070 simultaneous determinations of blood glucose, glucosylated hemoglobin and fructosamine as index of metabolic control in 519 diabetic patients].
Two thousand and seventy simultaneous determinations of glucose, glucosylated hemoglobin (HbA1) and plasma fructosamine have been performed in 519 diabetic patients in order to obtain a follow up index and metabolic profile. This retrospective study points out the difficulty of achieving a good metabolic control in diabetic patients. Although the determination of plasma glucosylated proteins (HbA1 and fructosamine) has meant a great improvement in diabetic control, the study of the correlation of the above mentioned.
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Neopterin is an intermediate purine metabolite which can be determined in serum and has been shown to be elevated in processes that stimulate cell mediated immunity. Neopterin serum levels have been measured in 37 patients diagnosed of boutonneuse mediterranean fever. ⋯ Neopterin levels normalized as the disease improved clinically. On the other hand, the highest levels were found in patients with a torpid evolution and appearance of complications.
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Revista clínica española · Sep 1989
[Vasculitis caused by hypersensitivity: an analysis of 60 patients].
Sixty cases of hypersensitivity vasculitis are revised analyzing their possible etiology, clinical course, analytical and histological alterations, evolution, and treatment. Thirty of these cases corresponded to Schönlein Henoch purpura (SH). The results of this subgroup (SH) are compared to other hypersensitivity vasculitis (HV).
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Pancreas transplantation offers the possibility of preventing the development and progression of diabetic lesions by adequate control of hydrocarbon metabolism. Moreover, the diabetic patient is freed from dietary and physical restrictions, as well as from insulin treatment. However, this is achieved at the expense of an immunosuppression not always free of risk. ⋯ The introduction of cyclosporine has greatly improved the transplantation results, achieving a 53% actuarial survival of the graft per year. Out of the different technics used, the one that yields best results is the transplantation of the whole organ, deriving the exocrine secretion to the urinary bladder. This method also enables early diagnosis of graft rejection by monitoring urine amylase.