Pediatric surgery international
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Pediatr. Surg. Int. · Nov 2012
ReviewA systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use.
A systematic review aimed to evaluate the efficacy and safety of aprotinin, epsilon-aminocaproic acid (EACA), and tranexamic acid (TXA) in reducing perioperative blood loss, risk for transfusion, and total perioperative transfusion volume in major pediatric surgery. Medline, Embase, and Cochrane Reviews were searched for relevant articles published from January 1990 to January 2012. Additional studies were identified by cross-referencing citations and extracting data from recent published reviews. ⋯ Antifibrinolytics are effective in reducing blood loss and transfusion requirements in major pediatric surgery. TXA and EACA also appear to have reasonable side-effect profiles. Application to craniofacial surgery is promising, though further investigation is necessary.
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Pediatr. Surg. Int. · Oct 2012
Comparative StudyLaparoscopic inguinal hernia repair in premature babies weighing 3 kg or less.
This retrospective study aims to evaluate the feasibility, safety and complication rate of laparoscopic inguinal hernia repair for small babies weighing 3 kg or less. ⋯ Laparoscopic inguinal hernia repair for babies weighing 3 kg or less is feasible, safe and perhaps even less technically demanding than open inguinal herniotomy.
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Pediatr. Surg. Int. · Aug 2012
Review Case ReportsSevere hyperphosphatemia after administration of sodium-phosphate containing laxatives in children: case series and systematic review of literature.
Sodium phosphate-containing laxatives are commonly used as first-line treatment option for constipation in children and adolescents. Hyperphosphatemia is an infrequent, but potentially life-threatening complication of laxative application. ⋯ Physicians should be alerted to the possibility of phosphate toxicity in children and adolescents treated with laxatives.
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Pediatr. Surg. Int. · Jul 2012
Case ReportsPediatric bilateral spontaneous pneumothoraces in monozygotic twins.
Primary spontaneous pneumothorax from subpleural bleb disease is an uncommon occurrence in pediatric patients. This is a rare case of monozygotic twins presenting at alternating intervals with a single-sided spontaneous pneumothorax, only to have it surgically corrected, and to present later with a subsequent contralateral pneumothorax. A review of familial spontaneous pneumothoraces occurring in children was queried for congenital or genetic syndromes. ⋯ While they are rare, some congenital syndromes have been identified. The HLA haplotype A2 B40, the gene encoding folliculin, Alph-1-antitrypsin, Marfan's syndrome, Ehlers-Danlos syndrome and Birt-Hogg-Dube syndrome have all been associated with familial spontaneous pneumothoraces. Physicians need to counsel family members to ensure appropriate observation and expedited treatment is not delayed.
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Pediatr. Surg. Int. · Jul 2012
ReviewThe timing of ostomy closure in infants with necrotizing enterocolitis: a systematic review.
The optimal timing of ostomy closure is a matter of debate. We performed a systematic review of outcomes of early ostomy closure (EC, within 8 weeks) and late ostomy closure (LC, after 8 weeks) in infants with necrotizing enterocolitis. ⋯ Evidence that supports early or late closure is scarce and the published articles are of poor quality. There is no significant difference between EC versus LC in the complication rate. This systematic review supports neither early nor late ostomy closure.