Journal of critical care
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Journal of critical care · Jun 2011
Randomized Controlled TrialMild hypothermia therapy reduces blood glucose and lactate and improves neurologic outcomes in patients with severe traumatic brain injury.
The study aimed to investigate the association between blood glucose or lactate and the outcomes of severe traumatic brain injury (TBI), and to evaluate the effect of mild hypothermia therapy on glucose and lactate levels. ⋯ Hyperglycemia after TBI was associated with poor clinical outcomes, but the predictive value of blood lactate level requires further investigation. Hypothermia therapy improves neurologic outcomes in patients with severe TBI, and reduction in blood glucose may be partially responsible for the improved outcomes.
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Journal of critical care · Jun 2011
Alveolar fluid clearance is faster in women with acute lung injury compared to men.
Studies suggest that there is a sex difference in the development and outcomes of acute lung injury (ALI). Few studies have directly addressed the association of sex and alveolar fluid clearance (AFC), a process that is critical to ALI resolution. ⋯ These findings may have significant implications for future ALI studies and potential therapies.
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Journal of critical care · Jun 2011
The epidemiology of acute respiratory failure in hospitalized patients: a Brazilian prospective cohort study.
The purpose of this study was to assess risk factors associated with the development of acute respiratory failure (ARF) and death in a general intensive care unit (ICU). ⋯ Acute respiratory failure represents a large percentage of all ICU patients, and the high mortality is related to some preventable factors such as the time to ICU admission.