Journal of critical care
-
Journal of critical care · Oct 2018
Observational StudyStrong ion difference and CVVH: Different response during nadroparin versus citrate anticoagulation.
To determine the effect on strong ion difference of citrate as an anticoagulant during continuous veno-venous hemofiltration (CVVH). ⋯ Citrate anticoagulation results in a persistently high SIG during CVVH compared to nadroparin. This is associated with the presence of unmeasured anions such as citrate in the systemic circulation.
-
Journal of critical care · Oct 2018
The evolution of activated protein C plasma levels in septic shock and its association with mortality: A prospective observational study.
Septic shock is commonly associated with hemostatic abnormalities. The endothelium-activated serine protease activated protein C (APC) plays a pivotal role in limiting coagulation and possesses anti-apoptotic and anti-inflammatory properties. We hypothesized that APC levels correlate with established coagulation parameters and provide prognostic information in patients with septic shock. ⋯ APC levels are increased in patients with septic shock and are correlated with established markers of coagulation. Elevated APC levels on admission are an independent predictor of mortality.
-
Journal of critical care · Oct 2018
Bedside percutaneous dilatational tracheostomy in patients outside the ICU: a single-center experience.
To assess the safety of medical-ward bedside percutaneous dilatational tracheostomy (GWB-PDT). ⋯ GWB-PDT is a feasible and safe solution for tracheostomies in general-ward ventilated patients.