Journal of critical care
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Journal of critical care · Oct 2018
Association between the neutrophil-to-lymphocyte ratio and neurological outcomes in patients undergoing targeted temperature management after cardiac arrest.
This study aimed to elucidate the association between the neutrophil-to-lymphocyte ratio (NLR) and neurological outcomes in out-of-hospital cardiac arrest (OHCA) patients treated with targeted temperature management (TTM). ⋯ An NLR ≥ 6 at 72 h after the ROSC is associated with poor neurological outcomes at 6 months after CA.
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Journal of critical care · Oct 2018
Observational StudyImpact of acute kidney injury on neurological outcome and long-term survival after cardiac arrest - A 10 year observational follow up.
Acute kidney injury (AKI) may be associated with short- and long-term patient morbidity and mortality. Therefore, the impact of AKI after cardiac arrest on survival and neurological outcome was evaluated. ⋯ Our data suggest that AKI is a major risk factor for a poor neurological outcome and a higher mortality after cardiac arrest. Further important risk factors were age, time to ROSC and high NSE.
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Journal of critical care · Oct 2018
Non-invasive positive pressure ventilation in lung transplant recipients with acute respiratory failure: Beyond the perioperative period.
The purpose of this study is to evaluate outcomes in MICU lung transplant recipients with acute respiratory failure treated with non-invasive positive pressure ventilation (NPPV) and identify factors associated with NPPV failure (need for intubation). ⋯ NPPV is a viable option for lung transplant recipients with acute respiratory failure. Extreme caution should be exercised when used in patients with high severity of illness (APACHE III >78) and/or severe hypoxemia (PaO2/FiO2 ≤ 151).
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Journal of critical care · Oct 2018
Evaluating the risk profile of quetiapine in treating delirium in the intensive care adult population: A retrospective review.
Dosing regimens of quetiapine to treat delirium in critically ill patients are titrated to effect, and may utilize doses higher than previously reported. This study aimed to assess the safety of quetiapine for this indication. ⋯ The dose of quetiapine has very little correlation with QTc and change from baseline. A small number of side effects were observed. Overall, titrating quickly to large doses of quetiapine is safe for treating delirium.
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Journal of critical care · Oct 2018
Observational StudyEvaluation of the efficacy of the National Early Warning Score in predicting in-hospital mortality via the risk stratification.
To investigate the efficacy of the National Early Warning Score (NEWS) in predicting in-hospital mortality. ⋯ NEWS is a simple and useful bedside tool for predicting in-hospital mortality. In addition, the rapid response team must consider other clinical factors as well as screening tools to improve clinical outcomes.