Journal of critical care
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Journal of critical care · Oct 2018
Clinical study of Presepsin and Pentraxin3 in critically ill children.
To assess the value of Presepsin and Pentraxin3 measurement in critically ill children. ⋯ Presepsin and Pentraxin3 are acute phase proteins potentially useful for monitoring critically ill children and diagnosing sepsis. Pentraxin3 is associated with mortality but modestly discriminates survivors from non-survivors. Presepsin is associated with certain indicators of disease severity. Larger studies are certainly required.
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Journal of critical care · Oct 2018
Observational StudySerum total antioxidant capacity during the first week of sepsis and mortality.
Higher circulating total antioxidant capacity (TAC) concentrations have been found in non-survivor than in survivor septic patients at moment of sepsis diagnosis. The objectives of this study were to determine whether serum TAC levels during the first week of sepsis are associated with lipid peroxidation, sepsis severity, and sepsis mortality, and whether could be used as a prognostic biomarker. ⋯ The new findings of our study were that serum TAC levels during the first week of sepsis are associated with lipid peroxidation, sepsis severity, and sepsis mortality, and that could be used as a prognostic biomarker.
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Journal of critical care · Oct 2018
Comparative StudySecondary EMR data for quality improvement and research: A comparison of manual and electronic data collection from an integrated critical care electronic medical record system.
This study measured the quality of data extracted from a clinical information system widely used for critical care quality improvement and research. ⋯ Manual validation processes of electronic data are complex in comparison to validation of traditional clinical documentation. This study represents a straightforward approach to validate the use of data repositories to support reliable and efficient use of high quality secondary use data.
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Journal of critical care · Oct 2018
Decision-making skills improve with critical care training: Using simulation to measure progress.
Health care professionals are expected to acquire decision-making skills during their training, but few methods are available to assess progress in acquiring these essential skills. The purpose of this study was to determine whether a simulation methodology could be used to assess whether decision-making skills improve during critical care training. ⋯ These findings provide evidence to support the validity of a simulation-based method to assess progress in decision-making skills. A simulation methodology could be used to establish a performance standard that determined a provider's ability to make independent decisions.
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Journal of critical care · Oct 2018
Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials.
We examined whether patients with acute respiratory distress syndrome (ARDS) lacking risk factors are enrolled in therapeutic trials and assessed their clinical characteristics and outcomes. ⋯ Patients with ARDS without identifiable risk factors are enrolled in therapeutic trials and may have better outcomes, including a higher proportion of rapidly resolving ARDS, than those with risk factors.