Journal of critical care
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Journal of critical care · Dec 2018
Risk of de novo infection following acute kidney injury: A retrospective cohort study.
Recent studies suggest that acute kidney injury (AKI) can affect distant organ function and increase non-renal complications. We determined whether AKI is associated with an increased risk of incident infections. ⋯ AKI was associated with incident in-hospital infections. However, newly occurring infections were not associated with an increased risk of mortality. Further studies are needed to understand how AKI affects distant organ function and associated clinical outcomes.
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Journal of critical care · Dec 2018
Meta AnalysisPrognostic value of plasma brain natriuretic peptide value for patientswith sepsis: A meta-analysis.
The aim of this meta-analysis was to clarify the diagnostic role of plasma BNP and NT-proBNP in predicting mortality for septic patients. ⋯ This meta-analysis indicates that both elevated plasma BNP and NT-proBNP have moderate predicts value for the mortality of septic patients, and the tested method and observation endpoint influence the results of BNP.
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Journal of critical care · Dec 2018
Observational StudyAssociation between death and loss of stage N2 sleep features among critically Ill patients with delirium.
Critically ill patients experience significant sleep disruption. In this study of ICU patients with delirium, we evaluated associations between the loss of stage N2 features (K-complexes, sleep spindles), grade of encephalopathy based on electroencephalography (EEG), and intensive care unit (ICU) outcomes. We hypothesized that loss of stage N2 features is associated with more severe grades of encephalopathy and worse ICU outcomes including death. ⋯ Loss of stage N2 features is common and associated with more severe encephalopathy and higher odds of death. The absence of either Stage N2 feature, K complexes or sleep spindles, may have important prognostic value.
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Journal of critical care · Dec 2018
Hospital case volume and clinical outcomes in critically ill patients with acute kidney injury treated with dialysis.
To determine whether patients with severe acute kidney injury who receive dialysis (AKI-D) experience better outcomes at centres that care for more patients with AKI-D. ⋯ There are no Centre volume survival associations in the management of AKI-D despite high mortality and dependence rate.
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Journal of critical care · Dec 2018
Right-to-left ventricular end diastolic diameter ratio in severe sepsis and septic shock.
The ratio of right ventricular end-diastolic diameter (EDD) to left ventricular EDD (RV/LV) is a measure predictive of right ventricular failure. We hypothesized that an increase in RV/LV would be associated with poor prognosis in severe sepsis and septic shock. ⋯ An increased RV/LV does not predict mortality in severe sepsis or septic shock.