Journal of critical care
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Journal of critical care · Dec 2019
Prospective validation and refinement of the APPROACH cardiovascular surgical intensive care unit readmission score.
The APPROACH cardiovascular surgical intensive care unit (CVICU) readmission score has excellent discrimination and calibration for CVICU readmission after discharge to a surgical ward; however, it has not been prospectively validated. ⋯ In a prospective validation cohort, the APPROACH CVICU readmission risk score had good discrimination and could be operationalized in future research and clinical practice.
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Journal of critical care · Dec 2019
Hemodynamic profiles following digoxin use in patients with sepsis in the ICU.
To explore the impact of digoxin on hemodynamic parameters in patients with sepsis and tachycardia admitted to the intensive care unit. ⋯ Early digoxin administration in patients with sepsis and tachycardia is uncommon but associated with improvements of hemodynamic parameters. These preliminary results will help formulate future hypotheses for focused trials on utility, efficacy and safety of digoxin in sepsis.
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Journal of critical care · Dec 2019
The incidence, predictors and outcomes of QTc prolongation in critically ill patients.
To study the incidence, predictors and outcomes of QTc prolongation (≥500 ms) during ICU admission. ⋯ A QTc ≥500 ms likely represents a marker of illness severity modulated by several risk factors, and carries no independent association with clinically-significant ventricular tachyarrhythmias. Thus, cessation of QT-prolonging medications to prevent arrhythmias may lack clinical benefit.
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The purpose of this study was to use an objective measure to evaluate sleep quality on the ward after ICU discharge in survivors of critical illness. ⋯ This study highlights the important role that future interventions might have in patients at high-risk of sleep disorders after critical illness.
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Journal of critical care · Dec 2019
Time of admission to intensive care unit, strained capacity, and mortality: A retrospective cohort study.
We sought to study the association between afterhours ICU admission and ICU mortality considering measures of strained ICU capacity. ⋯ Afterhours ICU admission and measures of strained ICU capacity were associated with crude but not adjusted ICU mortality.