Journal of critical care
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Journal of critical care · Oct 2020
Meta AnalysisExcess mortality risk from sepsis in patients with HIV - A meta-analysis.
Differences in HIV prevalence, access to antiretrovirals and ICU resources may result in wide variation in sepsis mortality in HIV patients. The aim of this study was to perform a meta-analysis to quantify the excess risk of sepsis mortality in HIV patients. ⋯ HIV increases the risk of sepsis mortality compared to seronegative individuals across all time periods and geographic areas. We note that this effect is more pronounced in patients with organ dysfunction.
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Journal of critical care · Oct 2020
Comparative StudyComparison of two frailty identification tools for critically ill patients: A post-hoc analysis of a multicenter prospective cohort study.
We aimed to describe the association of two frailty screening tools, the validated Clinical Frailty Scale (CFS) score and the recently described modified Frailty Index (mFI) in critically ill patients. ⋯ While the CFS and mFI showed low concordance, both showed good discrimination and predictive validity for hospital mortality. Both tools identify a subgroup of frail patients more likely to have worse clinical outcomes.
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Journal of critical care · Oct 2020
Randomized Controlled Trial Observational StudyDeterminants of Total/ionized Calcium in patients undergoing citrate CVVH: A retrospective observational study.
To identify potential determinants of the Total/ionized Ca ratio (T/iCa), a marker of citrate accumulation. ⋯ Besides citrate dose, a high pH and high phosphate, albumin and APACHE are also associated with a rising T/iCa.