Journal of critical care
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Journal of critical care · Feb 2020
Neuropsychiatric outcome in subgroups of Intensive Care Unit survivors: Implications for after-care.
Poor neuropsychiatric outcomes are common in survivors of critical illness but it is unclear what patient groups to target for interventions to improve mental health. We compared anxiety, depression, and post-traumatic stress disorder (PTSD) symptoms and health-related quality of life (HrQoL) across different subgroups of Intensive Care Unit (ICU) survivors. ⋯ This underlines the importance of prevention and treatment for neuropsychiatric symptoms in ICU survivors in general, not only in specific patient groups.
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Journal of critical care · Feb 2020
Gas exchange, specific lung elastance and mechanical power in the early and persistent ARDS.
Aim of this study was to evaluate the effect of acute respiratory distress syndrome (ARDS) duration on gas-exchange, respiratory mechanics, specific lung elastance and mechanical power. ⋯ The persistent phase of ARDS for 7-days did not affect the respiratory mechanics while significantly impaired the PaCO2 exchange.
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Journal of critical care · Feb 2020
The influence of clinical variables on the risk of developing chronic conditions in ICU survivors.
To assess the association of clinical variables and the development of specified chronic conditions in ICU survivors. ⋯ Clinical variables, especially the reason for ICU admission, are associated with the development of chronic conditions after ICU discharge. Therefore, these clinical variables should be considered when organizing follow-up care for ICU survivors.
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Journal of critical care · Feb 2020
Population pharmacokinetic model of Vancomycin based on therapeutic drug monitoring data in critically ill septic patients.
The present study aimed to establish a population pharmacokinetic model of vancomycin, including adult critically ill septic patients, with normal and impaired renal function. ⋯ The developed population vancomycin model may be used in estimating individual CL for adult critically ill septic patients, and could be applied for individualizing dosage regimens taking into account the continuous effect of CrCl.
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Journal of critical care · Feb 2020
Variation in red cell transfusion practice in the intensive care unit - An international survey.
Unclear recommendations in transfusion guidelines may possibly lead to inconsistency in treatment of patients admitted to the intensive care unit. This study aimed to uncover variation in red blood cell (RBC) transfusion decisions in the ICU worldwide. ⋯ Critical care physicians differed in outcome of RBC transfusion decisions and weighed patient characteristics differently. These findings indicate that variation in transfusion practice amongst critical care physicians exists.