Journal of critical care
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Journal of critical care · Aug 2021
Cardio-pulmonary-renal interactions in ICU patients. Role of mechanical ventilation, venous congestion and perfusion deficit on worsening of renal function: Insights from the MIMIC-III database.
Background Mechanical ventilation (MV) in ICU patients may impact hemodynamics and renal function. We aimed to describe the interactions of MV settings, hemodynamic parameters and worsening of renal function (WRF). Methods We included adult patients admitted for the first time in the ICU from the MIMIC-III database. ⋯ Conclusion In this large cohort of ICU patients, we observed a strong relationship between MV and WRF. PEEP was associated with WRF in MV patients. This association relied at least partly on renal venous congestion.
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Journal of critical care · Aug 2021
Hyperactive delirium in patients after non-traumatic subarachnoid hemorrhage.
Hyperactive delirium is common after subarachnoid hemorrhage (SAH). We aimed to identify risk factors for delirium and to evaluate its impact on outcome. ⋯ Our data indicate that hyperactive delirium is common after SAH patients and requires a certain degree of brain connectivity based ono the highest prevalence found in SAH patients with intermediate outcomes.
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Journal of critical care · Aug 2021
Impact of sterile leukocyturia on outcome of critically ill patients with severe acute kidney injury.
The role of immunological mechanisms on renal regeneration and functional recovery after an episode of Acute Kidney Injury (AKI) is still understudied. We aim to evaluate the impact of sterile leukocyturia on outcomes of critically-ill AKI patients. ⋯ Sterile leukocyturia was associated with different patient baseline and AKI characteristics and more persistent AKI by both KDIGO criteria. Sterile leukocyturia may represent a surrogate marker of renal inflammation during AKI.
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Journal of critical care · Aug 2021
Quality of life after sepsis and its association with mortality among sepsis survivors in South Korea: A population level cohort study.
This study aimed to investigate the incidence and effect of quality of life (QOL) change in Korean sepsis survivors. ⋯ We found that most sepsis survivors experienced a worsening in their QOL, which was associated with a higher risk of long-term mortality.
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Journal of critical care · Aug 2021
Acute Respiratory Distress Syndrome (ARDS) after trauma: Improving incidence, but increasing mortality.
Acute Respiratory Distress Syndrome (ARDS) is an infrequent, yet morbid inflammatory complication in injury victims. With the current project we sought to estimate trends in incidence, determine outcomes, and identify risk factors for ARDS and related mortality. ⋯ Although the incidence of ARDS after trauma appears to be declining, mortality is on the rise.