Journal of critical care
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Journal of critical care · Apr 2022
Multicenter StudyFamily perceptions of clinical research and the informed consent process in the ICU.
We investigated experiences of families who provide consent for research on behalf of a loved-one hospitalized in intensive care (ICU). ⋯ Acceptance of research opportunities by relatives on behalf of decisionally-incapacitated patients is underpinned by trust in the physicians and the legislative framework. Communication and the quality of information provided by the caregivers are key.
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Journal of critical care · Apr 2022
Discharge prescribing of enteral opioids in opioid naïve patients following non-surgical intensive care: A retrospective cohort study.
To estimate the incidence of new prescription of enteral opioids on hospital discharge in opioid naïve, non-surgical, critically ill patients and evaluate the risk factors associated with such occurrence. ⋯ A significant proportion of opioid naïve non-surgical ICU survivors receive a new opioid prescription on hospital discharge.
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Journal of critical care · Apr 2022
Observational StudyChanges in communication of end-of-life decisions in European ICUs from 1999 to 2016 (Ethicus-2) - a prospective observational study.
We investigated changes in communication practice about end-of-life decisions in European ICUs over 16 years. ⋯ End-of-life decisions are increasingly discussed but communication practices vary by region and follow a North-South gradient. Despite increased availability of information, patient preferences still remain unknown in every second patient. This calls for increased efforts to assess patient preference in advance and make them known to ICU clinicians.
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Journal of critical care · Apr 2022
Observational StudyTherapeutic drug monitoring of meropenem and piperacillin-tazobactam in the Singapore critically ill population - A prospective, multi-center, observational study (BLAST 1).
To determine percentage of patients with sub-therapeutic beta-lactam exposure in our intensive care units (ICU) and to correlate target attainment with clinical outcomes. ⋯ Current dosing practices may be suboptimal for ICU patients. Beta-lactam TDM may be useful.