Journal of critical care
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Journal of critical care · Apr 2019
Review Meta AnalysisRenal resistive index as predictor of acute kidney injury after major surgery: A systematic review and meta-analysis.
To determine the efficacy of Doppler renal resistive index in the prediction of acute kidney injury after major surgery. ⋯ Renal resistive index represents a useful marker with fair performance in the prediction of postoperative acute kidney injury. Future cohorts should establish the optimal timing of measurement and evaluate the most appropriate cut-off value that should be used in the clinical setting.
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Journal of critical care · Feb 2019
Review Meta AnalysisNoninvasive ventilation in acute hypoxemic respiratory failure: A systematic review and meta-analysis.
Evaluate current recommendation for the use of noninvasive ventilation (Bi-level positive airway pressure- BiPAP modality) in hypoxemic acute respiratory failure, excluding chronic obstructive pulmonary disease. ⋯ NIV showed a significant protective effect for intubation in immunosuppressed patients (cancer and transplants) and in patients with APE/CAP. However, the benefits of NIV for other etiologies are not clear and more trials are needed to prove these effects.
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Journal of critical care · Feb 2019
Review Meta AnalysisSafety and efficacy of iron therapy on reducing red blood cell transfusion requirements and treating anaemia in critically ill adults: A systematic review with meta-analysis and trial sequential analysis.
To evaluate the safety (risk of infection) and efficacy (transfusion requirements, changes in haemoglobin (Hb)) of iron therapy in adult intensive care unit (ICU) patients. ⋯ Iron therapy results in a modest increase in Hb. The current evidence is inadequate to exclude an important effect on transfusion requirements or infection.
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Journal of critical care · Dec 2018
Review Meta AnalysisEffect of adjunctive corticosteroids on clinical outcomes in adult patients with septic shock - a meta-analysis of randomized controlled trials and trial sequential analysis.
To assess the effect of corticosteroids on clinical outcomes in patients with septic shock. ⋯ Future trials are unlikely to detect a reduction in short-term mortality at a daily doses of 200 mg hydrocortisone. More evidence is required to confirm the beneficial effects of dual corticosteroid therapy.
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Journal of critical care · Dec 2018
Meta AnalysisEffect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis.
We aimed to classify nonpharmacological interventions used for preventing delirium in the intensive care unit (ICU), and estimate their effect size. ⋯ Nonpharmacological interventions were effective in reducing the duration and occurrence of delirium. Consistent application and development of nonpharmacological interventions for use in the ICU are important.