Journal of critical care
-
Journal of critical care · Oct 2020
Randomized Controlled Trial Observational StudyDeterminants of Total/ionized Calcium in patients undergoing citrate CVVH: A retrospective observational study.
To identify potential determinants of the Total/ionized Ca ratio (T/iCa), a marker of citrate accumulation. ⋯ Besides citrate dose, a high pH and high phosphate, albumin and APACHE are also associated with a rising T/iCa.
-
Journal of critical care · Oct 2020
ReviewUpdate I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19.
To assess efficacy and safety of chloroquine (CQ)/hydroxychloroquine (HCQ) for treatment or prophylaxis of COVID-19 in adult humans. ⋯ Patients with COVID-19 should be treated with CQ/HCQ only if monitored and within the context of high quality RCTs. High quality data about efficacy/safety are urgently needed.
-
Journal of critical care · Oct 2020
Multicenter StudyClinical course after identification of new-onset atrial fibrillation in critically ill patients: The AFTER-ICU study.
Epidemiological information is lacking after identification of new-onset atrial fibrillation (AF) in critically ill patients. This study aimed to describe the clinical course after the identification of new-onset AF. ⋯ Although the proportion of patients with AF continued to decrease with various treatments, these patients had high risk of death. Further research to assess the management of new-onset AF in critically ill patients is warranted.
-
Journal of critical care · Oct 2020
ReviewThe role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review.
To assess the efficacy and safety of suvorexant for the prevention of delirium during acute hospitalization. ⋯ Based on the reviewed literature, suvorexant has shown positive outcomes in the prevention of delirium during an acute hospitalization. Larger trials comparing the efficacy of suvorexant to other sleep modulating options are necessary to further delineate its role for the prevention of delirium.
-
Journal of critical care · Oct 2020
Observational StudyPsychotropic medication use in former ICU patients with mental health problems: A prospective observational follow-up study.
To describe the extent to which patients with mental health problems after admission to an Intensive Care Unit (ICU) initiate and use psychotropic medication. ⋯ Former ICU patients with mental health problems were almost four times more likely to use psychotropic medication than former ICU patients without these problems. Future research should investigate whether mental health problems are properly diagnosed and treated in former ICU patients.