Journal of critical care
-
Journal of critical care · Jun 2019
Randomized Controlled TrialThe effect of direct hemoperfusion with polymyxin B immobilized cartridge on meropenem in critically ill patients requiring renal support.
To evaluate the effect of direct hemoperfusion with polymyxin B immobilized cartridge (DHP-PMX) on meropenem pharmacokinetics in critically ill patients with sepsis requiring continuous venovenous hemofiltration (CVVH). ⋯ No significant effect of DHP-PMX on meropenem pharmacokinetics was observed among severe sepsis/septic shock patients during CVVH treatment.
-
Journal of critical care · Jun 2019
The relationship between self-report and performance-based measures of physical function following an ICU stay.
To examine relationships between self-report and performance-based measures of physical function in ICU patients randomized to standardized rehabilitation therapy (SRT) or usual care (UC). ⋯ Self-report and performance-based measures of physical function appear to assess different constructs at hospital discharge. Following recovery, these measures converge, but indicate different constructs are being assessed. As such, both self-report and performance-based measures of physical function should be used with ICU patients.
-
Journal of critical care · Jun 2019
ICU readmission of patients with cancer: Incidence, risk factors and mortality.
Few studies evaluated ICU readmission in cancer patients. This study aimed to describe the incidence and risk factors for ICU readmission in cancer patients and the association with mortality. ⋯ ICU readmission was associated with increased mortality. Mechanical ventilation and thrombocytopenia at the first admission were associated with ICU readmission.
-
Journal of critical care · Jun 2019
Association between strained ICU capacity and healthcare costs in Canada: A population-based cohort study.
Intensive care is resource intensive, with costs representing a substantial quantity of total hospitalization costs. Strained ICU capacity compromises care quality and adversely impacts outcomes; however, the association between strain and healthcare costs has not been explored. ⋯ Admissions to ICUs experiencing strain incur incremental costs, attributed to longer hospitalization and physician services.